Skip to main content

mitochondria Archives

Mitochondrial stress and hypertension

Jan. 12, 2021—Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential.

Read more


Assembling cell power plant machinery

Sep. 3, 2020—Tina Iverson and colleagues provide a structural view into the assembly of a protein machine essential for cellular energy production.

Read more


Transporter mutation alters cell energy

Feb. 20, 2020—A disease-associated mutation in a transporter protein causes cells to increase energy production, as if they are starving, Vanderbilt researchers have discovered.

Read more


Novel genetic study sheds new light on risk of heart attack

Oct. 11, 2018—Loss of a protein that regulates mitochondrial function can greatly increase the risk of myocardial infarction (heart attack), Vanderbilt scientists reported Oct. 3 in the journal eLife.

Read more


Mitochondrial mutations and disease

Feb. 22, 2018—New findings suggest that oxidative stress damages mitochondrial DNA, and they link this damage to a disease state.

Read more


Study sheds light on a ‘guardian’ protein of brain function

Feb. 19, 2015—Mitochondria not only are the cell’s main power producers, they are also the chief cooks and bottle washers.

Read more


Biomarker for diabetic eye disease

Sep. 26, 2014—A person’s mitochondrial gene “signature” could predict risk for diabetic retinopathy and guide early intervention strategies.

Read more


Mitochondrial mutations not random

Nov. 25, 2013—A study of mitochondrial DNA mutations suggests they result from a process that selects for particular mutations in certain tissues.

Read more


Model for MADD mitochondrial disease

Jul. 11, 2013—A zebrafish model of a severe mitochondrial disease will be useful for developing new therapeutic approaches.

Read more


Kids’ cells okay after mom’s cancer radiation

Jun. 22, 2012—Study finds no evidence of increased mitochondrial mutations in the children of women treated with radiation for cancer.

Read more


Evolution of cell’s power plant genome

May. 18, 2011—Vanderbilt researchers provide new information about how the genome inside our cellular “power plants” – the mitochondria – has evolved.

Read more


Recent Stories from VUMC News and Communications Publications

Vanderbilt Medicine
Hope
Momentum
VUMC Voice

more