mitosis Archives
VU study reveals factor’s new role in cell division, migration
Oct. 30, 2014—Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery.
Manager of mitotic stress
Dec. 13, 2013—The protein CK1 delays cell division to avoid the generation of defects that drive tumorigenesis.
Motor protein revs up cell division
Jul. 29, 2013—A motor protein that helps drive cell division may be a promising new target for cancer therapeutics.
Divvying up chromosomes
Dec. 16, 2011—Mitosis, or the separation of chromosomes during cell division, is driven by dynamic interactions between the kinetochore region on chromosomes and string-like structures called microtubules. A number of proteins, including the enzyme Cdk1, regulate these interactions, but it is unclear what kinetochore components such enzymes work upon. Kathy Gould, professor of cell and developmental biology,...