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mitosis Archives

VU study reveals factor’s new role in cell division, migration

Oct. 30, 2014—Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery.

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Manager of mitotic stress

Dec. 13, 2013—The protein CK1 delays cell division to avoid the generation of defects that drive tumorigenesis.

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Motor protein revs up cell division

Jul. 29, 2013—A motor protein that helps drive cell division may be a promising new target for cancer therapeutics.

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Divvying up chromosomes

Dec. 16, 2011—Mitosis, or the separation of chromosomes during cell division, is driven by dynamic interactions between the kinetochore region on chromosomes and string-like structures called microtubules. A number of proteins, including the enzyme Cdk1, regulate these interactions, but it is unclear what kinetochore components such enzymes work upon. Kathy Gould, professor of cell and developmental biology,...

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