Molecular Cell Archives
Researchers discover that protein switches functions to regulate DNA replication
Jul. 22, 2021—Vanderbilt biochemists have discovered what the DNA damage response protein RADX does — and how it does it.
Gene network for leukemia factor
Feb. 4, 2021—A new method speeds the analysis of factors that control gene expression from days to minutes, allowing researchers to uncover new targets for cancer treatment.
New method captures early viral-host protein interactions
May. 7, 2020—Researchers have developed a method to identify the primary interactions between incoming viral RNA genomes and host proteins.
New tool probes gene regulation
Feb. 6, 2020—Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation.
Study identifies protein’s role in chemotherapy resistance
Jul. 20, 2017—Researchers at Vanderbilt University Medical Center (VUMC) have discovered a protein that may lead to a new way to prevent resistance and improve outcomes for patients whose cancers have mutations in the tumor suppressor gene BRCA2.
Study helps clarify components of DNA ‘copy machine’
Nov. 12, 2015—Vanderbilt investigators have generated a “parts list” for the molecular machinery that duplicates DNA each time a cell divides. The research has implications for cancer therapies that target components of this machinery.
Study reveals how protein helps cells tolerate DNA damage
Jul. 16, 2015—Vanderbilt and Stanford investigators have discovered how a protein that's part of the DNA replication "machinery" helps cells tolerate DNA damage.
‘Docking stations’ on chromosomes new anti-cancer target
Mar. 26, 2015—Vanderbilt University researchers have discovered a cleft in a chromosome-binding protein that may hold the key to stopping most cancers in their tracks.