Molecular Physiology & Biophysics Archives
A key to calcium signaling
Feb. 11, 2020—Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles.
Reversing stress-related anxiety
Dec. 20, 2019—Inhibiting COX-2 — an enzyme associated with inflammation — could provide a novel therapeutic approach for stress-related psychiatric disorders.
Protein dynamics in the beating heart
Dec. 16, 2019—To study the dynamics of structural proteins in the heart, Vanderbilt investigators generated a cellular tool they expect will be useful for screening drugs that affect heart muscle contraction.
Blueprint for treating epilepsy
Nov. 14, 2019—Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders.
How salt increases blood pressure
Sep. 5, 2019—Vanderbilt researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension.
New window on fibrosis
Aug. 8, 2019—A previously unrecognized role for a cell surface receptor may open new therapeutic options for the treatment of fibrotic diseases.
New look at atherosclerosis
Jul. 11, 2019—A new imaging method makes it possible to directly measure cell division and changes in metabolism in atherosclerotic plaques.
Modulating stress circuits
Feb. 14, 2019—Danny Winder and colleagues demonstrate an interaction between two signaling pathways — and its impact on the activity of neurons that respond to stress.
Lean vs. obese adipose tissue cells
Dec. 13, 2018—A greater understanding of the mechanisms and cell types involved in returning adipose (fatty) tissue to the lean state may lead to more effective treatments for obesity.
Four researchers receive Young Investigator Grants
Nov. 15, 2018—Four Vanderbilt University researchers are among 200 recipients of this year’s Young Investigator Grants awarded by the Brain & Behavior Research Foundation to support “innovative ideas for groundbreaking neurobiological research.”
Obesity negates beneficial drug effects
Nov. 8, 2018—A drug that improves levels of “good” cholesterol may not be beneficial for obese individuals, Vanderbilt researchers have discovered.
Fat tissue’s “iron sink”
Sep. 27, 2018—Alyssa Hasty and colleagues demonstrated that immune cells called macrophages act in fat tissue to store iron and prevent iron toxicity.