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NCATS Archives

Lung damage protector

Apr. 12, 2013—Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue.

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Acetaminophen: protective in sepsis?

Mar. 28, 2013—In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen.

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HDL cholesterol impaired in kidney disease

Jan. 21, 2013—HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.

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A drug combo for ovarian cancer

Dec. 24, 2012—Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer.

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Low prenatal alcohol’s brain impact

Dec. 21, 2012—Even relatively low levels of in utero alcohol exposure impact fetal brain development, and the effects last into adulthood, study finds.

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Inherited lung disease no worse in offspring

Nov. 15, 2012—An inherited lung disease does not appear to have earlier onset and increased severity – a phenomenon called genetic anticipation – in successive generations.

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Kidney woes during heart failure

Nov. 8, 2012—Levels of the protein NGAL may be a good predictor of worsening kidney function in patients with acute heart failure.

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Bacterial signals in sarcoidosis

Nov. 6, 2012—Study adds evidence for infectious agents’ role in sarcoidosis, an inflammatory condition that can lead to respiratory failure and death.

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Toxin provides endometriosis clues

Nov. 2, 2012—Environmental toxins may contribute to endometriosis-related infertility by disrupting endometrial response to progesterone.

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More gene links to breast cancer risk

Oct. 19, 2012—Two newly identified gene variants linked to breast cancer may aid in predicting disease risk and targeting screening and prevention strategies.

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Cell entry ports for cold virus

Sep. 25, 2012—The respiratory virus HMPV uses its fusion (F) protein – which interacts with cellular receptors called integrins – to bind to and enter target cells.

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Parkinson’s therapy may impact language

Sep. 7, 2012—Deep brain stimulation used to treat Parkinson’s disease may impair some aspects of language processing, a recent study suggests.

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