NCATS Archives

Taking the ‘noise’ out of protein data

May. 1, 2013—Vanderbilt researchers have developed a novel algorithm to improve results from proteomic studies.

Fava beans’ impact on urine sodium

Apr. 29, 2013—Eating fava beans increases dopamine in blood and urine, but does not stimulate urinary sodium excretion.

A role for blood vessels in delirium?

Apr. 15, 2013—Dysfunction of the endothelial cells that line blood vessels may contribute to delirium and coma in critically ill patients – and could be a target for therapy.

Lung damage protector

Apr. 12, 2013—Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue.

Acetaminophen: protective in sepsis?

Mar. 28, 2013—In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen.

HDL cholesterol impaired in kidney disease

Jan. 21, 2013—HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.

A drug combo for ovarian cancer

Dec. 24, 2012—Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer.

Low prenatal alcohol’s brain impact

Dec. 21, 2012—Even relatively low levels of in utero alcohol exposure impact fetal brain development, and the effects last into adulthood, study finds.

Inherited lung disease no worse in offspring

Nov. 15, 2012—An inherited lung disease does not appear to have earlier onset and increased severity – a phenomenon called genetic anticipation – in successive generations.

Kidney woes during heart failure

Nov. 8, 2012—Levels of the protein NGAL may be a good predictor of worsening kidney function in patients with acute heart failure.

Bacterial signals in sarcoidosis

Nov. 6, 2012—Study adds evidence for infectious agents’ role in sarcoidosis, an inflammatory condition that can lead to respiratory failure and death.