NCATS Archives
Records point to drug-drug interaction
May. 7, 2018—Patients who take a cholesterol-lowering statin drug while taking the antibiotic daptomycin have increased risk of developing muscle weakness or a more severe form of muscle damage.
“Idling” cancer cells may return
Apr. 11, 2018—Vanderbilt investigators have discovered that cancer treatment induces an “idling” state for cells, which could promote resistance to treatment.
Long QT syndrome – revealed
Mar. 12, 2018—Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders.
Brain connections in schizophrenia
Mar. 9, 2018—Brain imaging studies have implicated the connection between two brain regions in the pathophysiology of schizophrenia.
Cannabis compound reduces seizures
Feb. 26, 2018—Cannabidiol (CBD) oils reduced seizures in patients with difficult-to-treat epilepsy, Vanderbilt investigators have found.
Muscular dystrophy clue
Feb. 9, 2018—Vanderbilt investigators have discovered a role for immune system T cells in slowing the decline in skeletal muscle function in patients with Duchenne muscular dystrophy.
A cataract-heart connection
Jan. 25, 2018—Studies of alpha-B crystallin in zebrafish could ultimately lead to improved treatment for cataracts and heart disease.
HDL and kidney injury after surgery
Jan. 17, 2018—Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered.
Obesity interventions: ideal dose?
Dec. 21, 2017—The optimal “dose” for behavioral interventions to treat childhood obesity are not clear, Vanderbilt researchers concluded after analyzing 133 clinical trial that occurred over the course of 17 years.
Sorting patient messages automatically
Dec. 20, 2017—Automated techniques can assist in understanding and managing growing volumes of messages sent through secure patient portals, Vanderbilt researchers found.
DNA damage repair: molecular insights
Dec. 5, 2017—Structural details about a protein involved in the repair of damaged DNA provide insight into xeroderma pigmentosum disorders, which are characterized by increased risk for skin cancer.
Salt, inflammation and hypertension
Nov. 13, 2017—Vanderbilt researchers have identified a pathway that links excess sodium, inflammation and hypertension.
