NCI Archives
H. pylori and lung cancer
Aug. 1, 2022—Specific biomarkers for H. pylori — a bacterium that infects the stomach — were associated with increased risk of lung cancer, Vanderbilt researchers have discovered.
Probing the tumor microenvironment
Jul. 12, 2022—Vanderbilt researchers used single-cell sequencing, imaging, and computational approaches to characterize the colonic tumor microenvironment, providing important insights to the components that play roles in colorectal tumor pathogenesis.
Ginseng intake and mortality
Jun. 20, 2022—Regular ginseng intake, particularly over a long duration, is associated with decreased risk of death from all causes, Vanderbilt researchers discovered in a large epidemiological study.
Breast cancer biomarkers of response
Jun. 16, 2022—Vanderbilt researchers have identified blood-based biomarkers associated with complete responses to neoadjuvant chemotherapy in patients with breast cancer.
Diabetes, cardiovascular drug targets
May. 24, 2022—Targeting receptors of the inflammatory lipid signaling molecule PGE2 may offer a new way to tackle both Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.
Study identifies first cellular “chaperone” for zinc, sheds light on worldwide public health problem of zinc deficiency
May. 17, 2022—A team led by Vanderbilt researchers has described and characterized the first zinc metallochaperone: a protein that puts zinc into other “client” proteins.
Computer eyeballs graft-vs-host disease
Apr. 7, 2022—A machine learning algorithm identified areas of skin affected by chronic graft-versus-host disease on par with clinicians, opening the door to streamlining and standardizing this measure of patient response to therapy.
New prognosis predictor and target for gastric cancer
Apr. 7, 2022—The protein CGA — a subunit of glycoprotein hormones — is a biomarker that predicts chemoresistance in gastric cancer and could be targeted along with EGFR to restore chemosensitivity.
Bots boost liver cancer outcome
Mar. 10, 2022—Vanderbilt researchers report that robotic-assisted surgery is comparable, if not superior, to laparoscopic surgery for early-stage liver cancer patients.
Melanoma treatment response
Feb. 24, 2022—Targeting the interaction between melanoma and immune cells could improve responses to targeted cancer therapies, Vanderbilt researchers found.
Diet and colorectal cancer risk
Feb. 14, 2022—Higher dietary intake of antioxidant compounds found in fruits, vegetables, teas and spices was associated with lower risk of colorectal cancer, and intake was lower among Black participants, potentially contributing to colorectal cancer health disparities.
Impaired neutrophils in autoimmunity
Jan. 27, 2022—Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity.