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neurology Archives

A speedier treatment for depression?

Jul. 11, 2022—Vanderbilt researchers used a computer-based search to identify a compound with promise as a new, mechanistically distinct and rapid-acting therapy for major depressive disorder.

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Study measures Alzheimer’s risk reductions associated with healthy lifestyles

Jun. 13, 2022—Reported June 13 in Neurology, an Alzheimer’s disease risk study from Vanderbilt University Medical Center measures significantly reduced risk associated with healthy lifestyles, including non-smoking, leisure-time exercise, low-to-moderate alcohol consumption, adequate sleep and healthy diet.

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Arterial stiffening linked to Alzheimer’s disease

Jul. 15, 2021—A research team from Vanderbilt University Medical Center reports in Neurology that greater stiffening of the aorta, the main artery in the human body, is associated in older adults with increased Alzheimer’s disease (AD) pathology as reflected in a range of neurochemical indicators measured in cerebrospinal fluid.

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VUMC team discovers new genetic disease

Jun. 3, 2021—Researchers at Vanderbilt University Medical Center have discovered a new genetic disease that causes a severe form of neurogenic orthostatic hypotension, a rapid drop in blood pressure upon standing that can cause fainting.

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Treating core Rett syndrome symptoms

Jun. 6, 2019—A new study published in Neurology reports the drug trofinetide has proven safe and effective in treating core symptoms of Rett syndrome in female children and adolescents.

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Small vessel disease MRI marker linked to worse cognitive health in older adults

Mar. 21, 2019—Enlarged perivascular spaces, which are commonly seen on brain MRIs in older adults, have important associations with worse cognitive performance, particularly information processing speed and executive function, according to a new study that challenges historical consideration that perivascular spaces are a harmless imaging marker.

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DBS treatment may slow tremor progression in early-stage Parkinson’s patients

Jun. 29, 2018—June 29, 2018 - Analysis of data from a clinical trial conducted at Vanderbilt suggests that deep brain stimulation (DBS) administered to patients with very early-stage Parkinson’s disease slowed the progression of rest tremor. The study, published June 29 in Neurology, is significant because it is the first evidence of a treatment that may possibly delay the progression of one of the cardinal features of Parkinson’s disease.

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Drug’s effectiveness for neurosarcoidosis studied

Nov. 16, 2017—A drug commonly prescribed for Crohn’s disease and rheumatoid arthritis is also effective for treating neurosarcoidosis, according to new research led by Vanderbilt neurologists.

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Research links heart function to brain’s memory center

Nov. 8, 2017—Research by a team of Vanderbilt University Medical Center (VUMC) scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer’s pathology first begins.

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Alzheimer’s study establishes way to measure resilience

Nov. 10, 2016—Vanderbilt researchers have established a new measure of resilience to cognitive impairment in people with asymptomatic Alzheimer’s disease.

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Iadecola set for Oates Lectureship in Clinical Pharmacology

Oct. 27, 2016—Costantino Iadecola, M.D., an expert in the molecular pathology of ischemic brain injury and neurodegeneration at Weill Cornell Medical College in New York, will present the 10th annual Meredith S. and John A. Oates Lectureship in Clinical Pharmacology on Nov. 3.

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Free symposium on autism, neuroscience and perceptual thinking

May. 18, 2016—“Neuro-diverse: A Symposium on Autism, Neuroscience and Perceptual Thinking” and an associated evening lecture – both free and open to the public – will take place on the Vanderbilt campus Monday, May 23.

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