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NHLBI Archives

How to get the biggest “bang” for the research “buck”

Dec. 7, 2023—Vanderbilt researchers are developing new methods to maximize what can be learned from clinical trials and cohort studies, while maintaining their rigor and reproducibility.

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Tracking lung macrophages

May. 4, 2023—A new technique will allow researchers to track subsets of immune cells that patrol and defend the lungs, to better understand the roles of these cells during lung inflammation, infection and injury.

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COVID alters respiratory microbiota

Apr. 25, 2023—COVID-19 infection alters the microbes of the upper respiratory tract for at least several weeks, and such disturbances could impact disease severity and be targets for therapeutic interventions.

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Genetics and chronic pain

Apr. 20, 2023—Polygenic risk scores — scores that reflect the influence of common genetic variants — could be used to predict the likelihood of developing chronic overlapping pain conditions and guide biomarker and targeted prevention efforts.

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The problem with the problem list

Apr. 10, 2023—Algorithms to infer missing problems and suggest that they be added to electronic health records improved problem list completeness, with benefits for clinical care, patient comprehension of health conditions and population health.

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COVID-19’s lingering impact on health

Apr. 6, 2023—A decline in cardiovascular fitness — measured by activity trackers in the All of Us research program — persisted among some groups even after COVID-related restrictions were relaxed, exacerbating health disparities.

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Cell-free hemoglobin in pulmonary hypertension

Mar. 6, 2023—Cell-free hemoglobin generated by the lungs may be a therapeutic target for treating pulmonary arterial hypertension, Vanderbilt researchers found.

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Diabetes drug may improve asthma

Feb. 21, 2023—New biomarker finding strengthens the case for using GLP-1R agonists to treat patients with Type 2 diabetes who also suffer from asthma.

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A new view of a cholesterol carrier

Feb. 7, 2023—Vanderbilt researchers developed a novel method to measure small RNAs carried by HDL and demonstrated that these molecules circulate in greater concentrations than previously believed and are likely to contribute to communication between immune cells.

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Gut microbiota and lung fibrosis

Feb. 6, 2023—Microorganisms residing in the gut influence the severity of lung fibrosis in mouse models, suggesting that modifying the gut microbiota may offer therapeutic benefit for patients.

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COVID-19 battle begins in the nose

Feb. 2, 2023—A high upper airway concentration of the virus that causes COVID-19 was associated with changes in gene expression that could impact disease progression, Vanderbilt researchers discovered.

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Study finds heart failure risk higher in rural areas

Jan. 25, 2023—A study co-led by Vanderbilt researchers found heart failure risk is 19% higher for adults living in rural areas of the U.S., as compared to urban areas, and 34% higher for Black men living in rural areas.

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