NHLBI Archives
Going after the ‘heart attack gremlin’
Sep. 8, 2016—A protein called Gremlin 2 controls the extent of inflammation after heart attack and may be a good therapeutic target.
Nervous system’s role in hypertension
Aug. 29, 2016—Increased activity of the “fight or flight” nervous system contributes to obesity-associated hypertension and may be a good therapeutic target for the disease.
Major grant enhances pulmonary fibrosis research
Aug. 18, 2016—Vanderbilt University Medical Center (VUMC) has received an $11 million program project renewal grant from the National Heart, Lung and Blood Institute to study the genetics and underlying biological mechanisms that lead to idiopathic pulmonary fibrosis (IPF).
In search of new asthma therapies
Aug. 15, 2016—A peptide molecule relaxes airway smooth muscle and may be a potential therapeutic for asthma that has become resistant to standard therapies.
Marrow cells’ role in pulmonary hypertension explored
Jul. 28, 2016—Cells from the bone marrow participate in the development of pulmonary arterial hypertension (PAH), and they can also protect against it, according to new findings from a team of Vanderbilt University Medical Center investigators.
Study shows opioids increase risk of death when compared to other pain treatments
Jun. 14, 2016—Long-acting opioids are associated with a significantly increased risk of death when compared with alternative medications for moderate-to-severe chronic pain, according to a Vanderbilt study released today in the Journal of the American Medical Assocation (JAMA).
Uninsured heart attack patients more likely to be transferred to another facility: study
Jun. 9, 2016—A new study finds that uninsured heart attack patients are more likely to be transferred.
Pulmonary fibrosis culprits
Jun. 6, 2016—New findings identify isoketal-modified proteins as a previously unrecognized feature of pulmonary fibrosis and as a potential therapeutic target for this disease.
Pregnancy-related heart disorder clues
Jun. 3, 2016—Vanderbilt researchers have identified biomarkers that could be useful for evaluating and treating pregnancy-related heart failure.
Improving natural killer cancer therapy
Apr. 29, 2016—A newly discovered mechanism that helps cancer cells avoid destruction by immune system cells may improve immunotherapies.
Switching breast cancer off
Apr. 14, 2016—Signaling by a receptor that is overexpressed in aggressive forms of breast cancer has been linked to glutamine metabolism, suggesting new anti-cancer therapeutic targets.
Immune defenses in asthma
Apr. 5, 2016—Vanderbilt researchers show that a certain factor negatively impacts the first-line responder cells in the lungs, providing one explanation for why patients with asthma are at greater risk for invasive bacterial disease.
