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NHLBI Archives

Boosting cell-based heart repair

May. 15, 2015—A metabolic change in adult stem cells makes them less “fit” for regenerative heart therapies, suggesting that strategies to prevent this response may boost the therapeutic usefulness of the cells.

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New player in heart cell growth

Apr. 6, 2015—Vanderbilt researchers have identified a new protein involved in heart cell growth, which could improve understanding of pathologic cardiac hypertrophy.

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Contributors to coronavirus ‘fitness’

Feb. 24, 2015—Understanding the role that host membrane modification plays in coronavirus replication is essential for developing novel approaches to block the viruses that cause SARS and MERS.

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Kidney disease impacts HDL function

Feb. 11, 2015—Chronic kidney disease impairs the protective functions of HDL, Vanderbilt researchers report this month.

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Cognitive changes in ‘standing’ syndrome

Jan. 13, 2015—Patients with orthostatic intolerance – problems when standing – have cognitive changes, even when seated, compared to healthy individuals.

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Does fish oil help prevent A-fib?

Jan. 9, 2015—Growing evidence suggests that fish oil, thought to directly prevent inflammation, oxidative stress and heart disease, may have limited clinical utility.

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Atrial disease and hypertension links

Dec. 18, 2014—New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease.

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Target for atherosclerosis therapies

Dec. 17, 2014—A newly identified “atheroprotective” gene is a tool for exploring plaque pathophysiology and may be a good target for therapies to slow atherosclerosis progression.

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Protein implicated in atherosclerosis

Nov. 25, 2014—Vanderbilt researchers have discovered a new target for the prevention of atherosclerotic plaque development and cardiovascular disease.

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Overactive stress response in obesity

Nov. 7, 2014—An overactive stress response contributes to the development of insulin resistance in obese individuals, and blocking it may be therapeutically beneficial.

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Peptide quells “genomic storm”

Oct. 28, 2014—A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection.

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Immune cells’ role in hypertension

Oct. 24, 2014—Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease.

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Recent Stories from VUMC News and Communications Publications

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer.  Don’t hesitate. Do it.

Momentum

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer. Don’t hesitate. Do it.

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

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