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NHLBI Archives

Pua lands NIH Director’s New Innovator Award

Oct. 1, 2019—Heather Pua, MD, PhD, one of 60 investigators to receive the 2019 NIH Director’s New Innovator Award, will explore a novel type of cell signaling by RNAs in allergic airway inflammation.

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Tailoring treatment for heart defect

Sep. 23, 2019—By defining the clinical and genetic factors that predict treatment response, Vanderbilt investigators aim to personalize therapy for a common heart complication in preterm infants.

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How salt increases blood pressure

Sep. 5, 2019—Vanderbilt researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension.

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New look at atherosclerosis

Jul. 11, 2019—A new imaging method makes it possible to directly measure cell division and changes in metabolism in atherosclerotic plaques.

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Study seeks to expand treatment options for rare airway disease

Jun. 13, 2019—Armed with $1.2 million in funding from the National Heart, Lung and Blood Institute (NHLBI), researchers at Vanderbilt University Medical Center are searching to understand the cause of a rare airway disease in hopes of developing better treatments.

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Cell-cell signals in developing heart

Jun. 10, 2019—Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease.

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Blueprint for rebuilding the heart

May. 9, 2019—Young-Jae Nam and colleagues are discovering how to express specific factors in connective tissue cells to turn them into heart muscle cells.

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The dynamic basement

May. 9, 2019—Vanderbilt scientists led by Andrea Page-McCaw have discovered a new way to analyze repair of basement membranes — important structural and functional components of tissues.

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Low oxygen and antibody responses

Apr. 25, 2019—Mark Boothby and colleagues are exploring the factors that contribute to antibody production and quality, which are key to our defense against pathogens and response to vaccines.

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Cardiac dysfunction in DMD

Mar. 28, 2019—The protein MMP7 is elevated in blood from patients with Duchenne muscular dystrophy who have cardiac dysfunction, suggesting that it may be a biomarker for heart disease severity.

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Drug interaction causes hypotension

Mar. 28, 2019—A muscle relaxing-drug and inhibitors of the metabolic enzyme CYP1A2 interact to cause severely low blood pressure and should not be co-prescribed, Vanderbilt investigators caution.

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Unraveling endocytosis

Mar. 28, 2019—New discoveries by Jason MacGurn and colleagues further understanding of the complex machinery that cells use take up substances from outside the cell.

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