NIA Archives
Alzheimer’s proteins in ICU survivors
Mar. 27, 2018—The cognitive impairment that affects patients who survive a stay in the ICU does not appear to have a similar mechanism to Alzheimer’s disease, Vanderbilt researchers have discovered.
Vitamin C deficiency and mitochondrial dysfunction in Alzheimer’s disease
Dec. 1, 2017—Recent findings suggest that vitamin C deficiency could contribute to Alzheimer’s disease, suggesting that avoiding deficiency through diet and supplementation could protect against disease onset.
Pain and Alzheimer’s disease
Sep. 5, 2017—Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked.
Oxidative stress on the brain
Aug. 23, 2017—Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders.
Clue to pulmonary hypertension
Apr. 13, 2017—Vanderbilt investigators have studied the relationship between race, cardiometabolic traits and pulmonary hypertension.
A molecular clue to longevity
Mar. 31, 2017—In budding yeast, accumulation of a certain type of RNA in the nucleus increased life span, offering a new clue to longevity.
Delirium in the ED
Mar. 20, 2017—Interventions for delirium in the emergency department setting are needed to preserve patients’ long-term function and cognition, Vanderbilt investigators have found.
Dementia linked to diet
Feb. 7, 2017—Some memory deficits observed in Alzheimer’s disease may be due to co-morbid illnesses – not the disease itself – and may be reversed by lifestyle changes or pharmacologic interventions.
Risk factors for delirium
Sep. 13, 2016—High levels of blood markers for vascular endothelial dysfunction were associated with longer periods of confusion in ICU patients, Vanderbilt researchers have discovered.
Aging insights from budding yeast
Apr. 2, 2015—The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered.
New target for breast cancer therapy
Jul. 31, 2014—The protein MTBP is overexpressed in an aggressive type of breast cancer, and it regulates another protein implicated in many cancer types, suggesting that it may be a good target for new therapeutics.
Delirium increases long-term disability
Mar. 17, 2014—Patients who suffer a longer duration of delirium in the intensive care unit are more likely to experience long-term disability after discharge.
