NIA Archives
Imaging guides Alzheimer gene search
Feb. 28, 2014—Using imaging data, Vanderbilt researchers discovered an association between a gene pair and brain changes in Alzheimer’s disease.
Antioxidants promising for rare disorder
Feb. 6, 2014—The antioxidant vitamin E prevented the buildup of toxic products in a model of a rare genetic disorder, suggesting new strategies for therapeutic development.
A pain in the … genes
Jan. 10, 2014—Vanderbilt researchers have discovered that variation in the gene encoding the potassium channel GIRK1 plays a role in modulating human pain perception.
Cancer drug enhances cognition
Dec. 16, 2013—The breast cancer drug tamoxifen improves cognitive performance in post-menopausal women.
Mitochondrial mutations not random
Nov. 25, 2013—A study of mitochondrial DNA mutations suggests they result from a process that selects for particular mutations in certain tissues.
Amish aid study of Parkinson genetics
Nov. 11, 2013—Amish populations are valuable for genetic research because of their isolation, shared ancestry and homogeneous lifestyles.
Metabolic profiling of vision loss
Sep. 27, 2013—A panel of metabolites – small molecules that are part of metabolic processes – that are unique to macular degeneration will shed light on the disease and aid diagnosis.
Amish aid search for Alzheimer’s genes
Oct. 11, 2012—An analysis of Amish populations revealed novel risk genes for late-onset Alzheimer disease.
Pathways to delirium in the ICU
Apr. 17, 2012—Study suggests that the “kynurenine” biochemical pathway could be a target for reducing delirium and coma in critically ill patients.