NIAAA Archives
Personalized pain management
Feb. 28, 2019—Understanding how natural brain chemicals with pain-relieving properties interact with administered opioids may guide personalized approaches for pain management.
Modulating stress circuits
Feb. 14, 2019—Danny Winder and colleagues demonstrate an interaction between two signaling pathways — and its impact on the activity of neurons that respond to stress.
Award bolsters study of alcohol’s impact on the brain
Jul. 28, 2016—Vanderbilt University researcher Danny Winder, Ph.D., has received a MERIT Award from the National Institute of Alcohol Abuse and Addiction (NIAAA), part of the National Institutes of Health, for his contributions to understanding how alcohol affects the brain.
COX-2 blocker could help PTSD
May. 12, 2016—COX-2 inhibitors – used clinically to reduce inflammation and pain – may find new applications for treating PTSD and other stress-related psychiatric disorders like major depression.
Anti-inflammatory protein “rheostat” sheds light on leaky blood vessels
Aug. 1, 2014—Vanderbilt researchers have discovered that the protein CRADD counteracts inflammatory injury to endothelial cells, which could assist the development of new therapies for inflammatory vascular disorders.
New target for stopping inflammation
Oct. 11, 2013—Importin alpha 5, a member of a family of proteins that “shuttle” other proteins into the nucleus, is a potential new target for drugs to treat inflammatory diseases.
Nuclear shield against cell death
Aug. 8, 2013—The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold.
Low prenatal alcohol’s brain impact
Dec. 21, 2012—Even relatively low levels of in utero alcohol exposure impact fetal brain development, and the effects last into adulthood, study finds.
Alcohol’s molecular mediators
Jan. 23, 2012—Therapeutic agents focusing on the brain region involved in stress-induced relapse may be effective in preventing relapse in patients with alcohol use disorders.
