NIAMS Archives
Bone matrix changes during aging
Jan. 10, 2020—Changes to the bone matrix that occur during aging may point to novel targets for treating osteoporosis.
The dynamic basement
May. 9, 2019—Vanderbilt scientists led by Andrea Page-McCaw have discovered a new way to analyze repair of basement membranes — important structural and functional components of tissues.
Drug interaction causes hypotension
Mar. 28, 2019—A muscle relaxing-drug and inhibitors of the metabolic enzyme CYP1A2 interact to cause severely low blood pressure and should not be co-prescribed, Vanderbilt investigators caution.
Repairs in the basement membrane
Aug. 2, 2018—Studies in fruit flies have shed light on how the basement membrane — a sheet-like scaffold that wraps around most animal tissues — is repaired after being damaged.
How the skin protects
Apr. 19, 2018—Treatments for common skin conditions such as atopic dermatitis may be improved by understanding the enzymes responsible for forming the skin’s water-tight barrier.
Probing the genetics of autoimmunity
Jul. 21, 2017—Vanderbilt researchers have found that non-coding regions of the genome appear to contribute to the risk of autoimmune diseases and may represent attractive therapeutic targets.
Improving wound healing
Nov. 8, 2016—Vanderbilt researchers have shown that an injectable material improves wound healing and may be useful for large skin wounds such as those in patients with diabetes.
Rheumatoid subtypes explored by PheWAS
Oct. 7, 2016—A computer-based method pioneered at Vanderbilt is being used to compare subtypes of rheumatoid arthritis.
Wound-healing scaffolds
Jan. 27, 2016—The elasticity of a scaffold used for healing skin wounds is a key factor in promoting regeneration versus scarring.
Neurofibromin fine-tunes bone growth
May. 6, 2015—The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered.
Bone healing therapy for NF1 fractures
Sep. 11, 2014—A combination treatment delivered to the site of fractures may improve bone healing in patients with the genetic disease neurofibromatosis type-1.
Novel treatment strengthens bones in genetic disease
Aug. 7, 2014—An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.
