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NIDDK Archives

Cell changes en route to stomach cancer

Sep. 26, 2013—Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer.

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Probing intestinal immune cell roles

Aug. 28, 2013—A new in vitro system will allow investigators to explore how immune system T cells develop specialized functions.

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Tumor factor spurs blood vessel growth

Aug. 26, 2013—A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.

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Noninvasive test detects stomach bug

Aug. 12, 2013—A noninvasive test can be used to identify the presence of Helicobacter pylori and evaluate its virulence, which will be useful in areas with high rates of H. pylori-associated gastric cancer.

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Matrix member key to insulin resistance

Jun. 6, 2013—A component of the extracellular matrix that surrounds cells plays a role in insulin resistance and may be a good therapeutic target.

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Salt revs stomach bug’s cancer impact

May. 13, 2013—A high-salt diet worsens the carcinogenic effects of Helicobacter pylori, a bacterium that colonizes the stomachs of half of the world’s population.

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Dual-action enzyme protects esophagus

May. 9, 2013—An antioxidant enzyme also functions as a tumor suppressor to limit cancer development in the esophagus.

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Food variety drives overeating in mouse model of obesity syndrome

Apr. 25, 2013—Dietary variety – not high-fat or sugary foods – appears to stimulate overeating in a mouse model of an inherited obesity syndrome.

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‘Longevity’ gene aids kidney survival

Apr. 17, 2013—A gene associated with cell survival and longevity may protect the kidney from acute injury.

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“Silent” B cells trigger autoimmunity

Apr. 3, 2013—Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

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Plant compound stops colon cancer cells

Mar. 29, 2013—Berberine, an herbal remedy for diarrhea and intestinal parasites, may be useful in colon cancer therapy.

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IRF6 on the tip of tongue development

Mar. 18, 2013—The factor IRF6 plays important roles in the development of the tongue.

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