NIDDK Archives
Obesity negates beneficial drug effects
Nov. 8, 2018—A drug that improves levels of “good” cholesterol may not be beneficial for obese individuals, Vanderbilt researchers have discovered.
Low health literacy associated with early death for cardiovascular patients
Nov. 7, 2018—Patients hospitalized with a cardiovascular event are more likely to die within one year if they have low health literacy, according to a Vanderbilt University Medical Center study released this week in Mayo Clinic Proceedings.
Team’s findings show glutamine metabolism affects T cell signaling
Nov. 1, 2018—The cellular nutrient glutamine launches a metabolic signaling pathway that promotes the function of some immune system T cells and suppresses others, Vanderbilt researchers have discovered.
Targeting diabetic kidney disease
Oct. 12, 2018—Pathways activated by the epidermal growth factor receptor may be attractive targets to treat diabetic kidney disease, according to new findings from Vanderbilt investigators.
Insulin accelerant
Oct. 11, 2018—It’s possible to increase the permeability of blood vessels and accelerate insulin action in muscle, Vanderbilt researchers have discovered.
Fat tissue’s “iron sink”
Sep. 27, 2018—Alyssa Hasty and colleagues demonstrated that immune cells called macrophages act in fat tissue to store iron and prevent iron toxicity.
Diabetes drug may prevent cancer
Sep. 14, 2018—The research suggests that metformin should be further studied clinically for the prevention of liver cancer.
How microvilli form
Sep. 13, 2018—A protein called IRTKS helps build the microvilli that form the border of cells in the intestines, explaining why the protein is a frequent target of gut pathogens.
Healthy antibodies reverse diabetes
Sep. 13, 2018—Vanderbilt researchers have discovered that IgM-type antibodies appear to play a protective role to prevent the development of type 1 diabetes — and that purified IgM antibodies can reverse the disease.
Unleashing TIGER on small RNAs
Sep. 5, 2018—Vanderbilt investigators have developed a new analytical tool to identify, quantify and analyze small RNAs.
Investigators find that bile acids reduce cocaine reward
Aug. 30, 2018—Bile acids — gut compounds that aid in the digestion of dietary fats — reduce the desire for cocaine, according to a new study by researchers at Vanderbilt and the University of Alabama at Birmingham.
YAP after acute kidney injury
Aug. 16, 2018—Activation of the signaling protein YAP may be a target for treating acute kidney injury, which affects up to 20 percent of hospitalized patients.
