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NIGMS Archives

Aging insights from budding yeast

Apr. 2, 2015—The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered.

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Antibiotics with anticancer potential

Feb. 25, 2015—A series of experimental antibiotics may be a good starting point for developing new anticancer drugs.

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‘Stretched’ cells promote cancer

Feb. 19, 2015—Mechanical stress appears to be a critical factor in activating normal tissue-associated fibroblasts to generate cancer-associated fibroblasts.

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Gene profile predicts metastasis

Feb. 9, 2015—A specific gene expression profile represents a novel, biologically relevant “signature” for identifying colon cancers with high risk of metastatic recurrence, Vanderbilt researchers have found.

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Copper toxicity and Parkinson’s

Feb. 5, 2015—A genetic predisposition to Parkinson’s disease makes neurons more vulnerable to the toxicity of heavy metals such as copper.

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New clue to a devastating disease

Jan. 28, 2015—New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease.

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Immune response depends on force

Jan. 26, 2015—New studies explain how T-cell receptors use force to recognize and protect us against pathogens.

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Enzyme affects tumor metastasis

Jan. 8, 2015—A protein that degrades the “matrix” between cells participates in the development of lung metastases from primary breast cancer in mouse models and may be a good target for breast cancer treatment.

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Atrial disease and hypertension links

Dec. 18, 2014—New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease.

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Retinal neuron survival in glaucoma

Dec. 16, 2014—Understanding how the protein TRPV1 helps neurons survive after glaucoma-related stressors could lead to new therapeutic strategies for glaucoma and other neurodegenerative conditions.

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New tools to probe manganese biology

Nov. 26, 2014—Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.

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VU study reveals factor’s new role in cell division, migration

Oct. 30, 2014—Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery.

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Recent Stories from VUMC News and Communications Publications

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer.  Don’t hesitate. Do it.

Momentum

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer. Don’t hesitate. Do it.

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

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