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NIGMS Archives

E-records shed light on drug response

Mar. 31, 2014—Electronic medical records linked to DNA biobanks are a valid resource for defining and understanding the genetic factors that contribute to drug response.

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A new way to target cancer-driver Ras

Mar. 13, 2014—Vanderbilt researchers have discovered small molecules that turn off cancerous Ras signals in a new way.

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Dismantling staph’s drug resistance

Mar. 3, 2014—Targeting the enzyme FosB could make antibiotic-resistant staph bacteria sensitive to the antibiotic fosfomycin.

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Imaging guides Alzheimer gene search

Feb. 28, 2014—Using imaging data, Vanderbilt researchers discovered an association between a gene pair and brain changes in Alzheimer’s disease.

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Human and Helicobacter co-evolution

Jan. 23, 2014—by Denise Anthony A Vanderbilt University-led research team has solved a long-standing riddle: Why do people of mostly Amerindian ancestry in the Andes have a gastric cancer rate that is 25 times higher than that of fellow Colombians of mostly African descent only 124 miles away on the coast? The answer is disruption of co-evolution...

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A pain in the … genes

Jan. 10, 2014—Vanderbilt researchers have discovered that variation in the gene encoding the potassium channel GIRK1 plays a role in modulating human pain perception.

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Manager of mitotic stress

Dec. 13, 2013—The protein CK1 delays cell division to avoid the generation of defects that drive tumorigenesis.

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Mitochondrial mutations not random

Nov. 25, 2013—A study of mitochondrial DNA mutations suggests they result from a process that selects for particular mutations in certain tissues.

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What makes us human?

Nov. 22, 2013—Using computational tools to search for the genetic basis of what makes us human, Vanderbilt Assistant Professor of Biomedical Informatics Tony Capra and colleagues at the University of California-San Francisco have identified promising candidate regions.

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Therapeutic target for synovial sarcoma

Nov. 21, 2013—Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer.

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Targets of SIN drive cell division

Oct. 25, 2013—Vanderbilt researchers have identified a key regulator of cell division.

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Shining a light on night blindness

Oct. 24, 2013—Vanderbilt researchers are studying how mutations in the receptor for light, rhodopsin, cause light blindness.

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Recent Stories from VUMC News and Communications Publications

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer.  Don’t hesitate. Do it.

Momentum

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer. Don’t hesitate. Do it.

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

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