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NIGMS Archives

Colon cancer’s cellular crossroads

Mar. 16, 2012—New information about signaling pathways involved in colorectal cancer could aid in assessing prognosis and identifying new therapeutic targets for the disease.

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‘Detangler’ binds, bends and cuts DNA

Mar. 2, 2012—New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents.

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On the tail of RSV infection mechanism

Feb. 15, 2012—New details about the life cycle of respiratory syncytial virus (RSV) could aid the development of therapies to combat this leading cause of serious illness in infants and the elderly.

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Meds’ benefits differ in dialysis patients

Jan. 5, 2012—About half of kidney patients will die from heart disease within five years of starting dialysis, yet patients with kidney failure are rarely included in heart disease research. Jorge Gamboa, M.D., T. Alp Ikizler, M.D., and Nancy Brown, M.D., completed a small study that suggests a more personalized approach to selecting medication for heart disease...

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Divvying up chromosomes

Dec. 15, 2011—Protein helps ensure proper division of chromosomes during cell division.

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Virus-linked cancer gets help from host

Dec. 15, 2011—Host cell protein may be a target for strategies to limit spread of virus-induced squamous cell cancers.

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Let there be light and melatonin

Nov. 4, 2011—Light and the hormone melatonin may play important roles in the developing brain.

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Heart protein may be target for colon cancer therapies

Oct. 7, 2011—A protein critical in heart development may also play a part in colon cancer progression.

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