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NIGMS Archives

Probing the genetics of autoimmunity

Jul. 21, 2017—Vanderbilt researchers have found that non-coding regions of the genome appear to contribute to the risk of autoimmune diseases and may represent attractive therapeutic targets.

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NOTCH1 role in heart development

Jul. 3, 2017—The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition.

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Genetics of lung cancer survival

Jun. 29, 2017—Vanderbilt investigators have conducted a first-of-its-kind genome-wide association study of lung cancer survival in African-Americans.

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Repriming replication roadblocks

Jun. 12, 2017—New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.

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Protein structure may aid in treating Alzheimer’s disease

Apr. 27, 2017—A new protein structure may guide the development of Alzheimer's therapeutics.

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A molecular clue to longevity

Mar. 31, 2017—In budding yeast, accumulation of a certain type of RNA in the nucleus increased life span, offering a new clue to longevity.

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A target to heal tiny lungs

Feb. 23, 2017—The protein beta-catenin may be a good target for therapies to treat lung disease that is a common complication of preterm birth.

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Pathology of septic shock

Feb. 8, 2017—The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection.

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Bacterial signaling systems

Feb. 3, 2017—Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance.

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New target for chronic infection

Feb. 2, 2017—An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered.

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Improving vaccine formulations

Jan. 20, 2017—The compound MPLA is an attractive vaccine component, designed to elicit a robust immune response.

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Single-cell analysis of solid tumors

Dec. 12, 2016—A new method will make it possible to study solid tumors and healthy tissues using mass cytometry.

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Recent Stories from VUMC News and Communications Publications

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer.  Don’t hesitate. Do it.

Momentum

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer. Don’t hesitate. Do it.

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

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VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

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