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pathology microbiology and immunology Archives

Study identifies monoclonal antibodies that may neutralize many norovirus variants

Jul. 16, 2021—Researchers at Vanderbilt University Medical Center (VUMC) and the Baylor College of Medicine in Houston, Texas, have taken a big step toward developing targeted treatments and vaccines against a family of viruses that attacks the gastrointestinal tract.

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Therapeutic antibodies for hantavirus

May. 24, 2021—Vanderbilt Vaccine Center researchers have isolated monoclonal antibodies against hantaviruses, an emerging source of human disease with pandemic potential.

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Heparin, platelets discouraged as treatment for blood clots after COVID vaccine

May. 12, 2021—Heparin and platelets are discouraged as treatment for patients who develop blood clots in the brain and low platelet counts 6-15 days after receiving Johnson & Johnson’s Janssen COVID-19 vaccine, following a clinical investigation review of 12 U.S. cases conducted by the CDC and institutions including Vanderbilt University Medical Center.

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Study finds that regulatory protein prevents signaling that triggers cell death

May. 6, 2021—A protein implicated in neurodegenerative diseases including amyotrophic lateral sclerosis prevents the activation of an innate immune response that leads to cell death, Vanderbilt researchers have discovered.

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Study revises understanding of cancer metabolism

Apr. 7, 2021—Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.

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Novel way to neutralize Rift Valley Fever Virus

Apr. 1, 2021—The discovery of monoclonal antibodies that neutralize Rift Valley Fever Virus — an emerging infection with pandemic potential — lays the foundation for future therapeutic antibody development.

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Team studies new use for pulmonary hypertension drug

Mar. 25, 2021—An FDA-approved medication enhances the function of T regulatory cells (Treg), a class of immune cells that restrains the immune response, Vanderbilt investigators have discovered.

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Prostate cancer microenvironment

Mar. 23, 2021—Distinct cancer-associated fibroblasts in the prostate tumor microenvironment may influence tumor progression and could point to new therapeutic targets.

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Temperature, newts and a skin-eating fungus

Mar. 8, 2021—Salamanders are more sensitive to a skin-eating fungus at colder temperatures, pointing to locations of North America where pathogen invasion is most likely.

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Calcification after severe injury

Feb. 23, 2021—Vanderbilt researchers have linked bone-related complications of severely injured patients — findings that could help minimize these complications.

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Seegmiller named to new pathology, laboratory medicine leadership posts

Feb. 18, 2021—Adam Seegmiller, MD, PhD, has been named the inaugural vice chair for Clinical Affairs in the Department of Pathology, Microbiology and Immunology as well as executive medical director of the newly formed Pathology and Laboratory Medicine — Clinical Service Center.

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VUMC postdoctoral scientist named HHMI Hanna Gray Fellow

Feb. 18, 2021—Valeria Reyes Ruiz, PhD, a postdoctoral fellow in the Department of Pathology, Microbiology and Immunology, has been selected as a 2020 Hanna Gray Fellow by the Howard Hughes Medical Institute (HHMI).

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