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pathology microbiology and immunology Archives

Probing innate immunity

May. 19, 2020—Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.

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Antibodies eye Pacific Island “fever”

May. 14, 2020—Vanderbilt Vaccine Center team isolates monoclonal antibodies against Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months.

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The adaptable anthrax bacterium

May. 14, 2020—Vanderbilt researchers discover how anthrax bacterium defends itself against structural damage and resists the toxicity of the antimicrobial drug targocil.

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New method captures early viral-host protein interactions

May. 7, 2020—Researchers have developed a method to identify the primary interactions between incoming viral RNA genomes and host proteins.

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Price’s old laboratory recipe book proves to be invaluable

Apr. 30, 2020—Howard Price has a decades-old green notebook he keeps in his office at Vanderbilt University Medical Center, and when a shortage of a critical laboratory supply nearly brought testing for SARS-CoV-2, the virus that causes COVID-19, to a halt at the Medical Center, the notebook’s contents quickly became invaluable.

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Antibody finding raises hopes for Marburg, COVID-19 treatments

Apr. 30, 2020—Monoclonal antibodies against Marburg virus — a more lethal cousin of the RNA virus that causes COVID-19 — may aid in the development of antibody “cocktails” to counter viral infection.

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Collaboration key to rapid expansion of lab test capacity

Apr. 23, 2020—The rapid ramping up of SARS-CoV-2 testing at VUMC reflects the dedication of the professionals who work in the Clinical Laboratory and also their collaboration with colleagues in research laboratories throughout VUMC.

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VUMC seeks plasma donations from recovered COVID-19 patients

Apr. 14, 2020—Vanderbilt University Medical Center is recruiting volunteers who have tested positive for COVID-19 and fully recovered to donate plasma to help those who are currently ill with the virus as part of a new research study.

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Research team awarded $9 million to study extracellular RNA in colorectal cancer

Apr. 9, 2020—The NCI program project grant is supporting multiple projects that aim to define fundamental biological principles about extracellular RNA signaling and the development and aggressiveness of colorectal cancer, the second leading cause of cancer death in the United States.

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Diagnostic testing for genetic disorders now available on site

Mar. 12, 2020—Vanderbilt University Medical Center has opened a Clinical Genomics Laboratory to provide diagnostic testing for genetic disorders.

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Bordenstein honored by Genetics Society of America

Feb. 27, 2020—The Genetics Society of America has recognized Seth Bordenstein, PhD, an evolutionary geneticist and microbiologist at Vanderbilt, for an initiative that brings real-world scientific research into middle school, high school and college biology classes.

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Looking through MudPIT for protein interactions

Feb. 25, 2020—The identification of novel protein interactions and sites of modification in proteins involved in mRNA translation adds to understanding of a process that is an important therapeutic target.

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Recent Stories from VUMC News and Communications Publications

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Hope
Momentum
VUMC Voice

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