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Pew Biomedical Scholars Archives

Study finds that regulatory protein prevents signaling that triggers cell death

May. 6, 2021—A protein implicated in neurodegenerative diseases including amyotrophic lateral sclerosis prevents the activation of an innate immune response that leads to cell death, Vanderbilt researchers have discovered.

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Cellular antiviral defenses

Jul. 23, 2020—A cellular RNA quality control mechanism was known to restrict replication of RNA viruses. Vanderbilt researchers have discovered it is also antiviral against DNA viruses.

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RNA processing and antiviral immunity

Dec. 13, 2018—John Karijolich and colleagues have discovered a link between cellular RNA processing and the innate cellular immune response to viral pathogens.

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Karijolich named 2018 Pew Biomedical Scholar

Jun. 14, 2018—John Karijolich, PhD, assistant professor of Pathology, Microbiology, and Immunology at Vanderbilt University Medical Center, has been named a Pew Biomedical Scholar by The Pew Charitable Trusts.

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