pharmacogenomics Archives
Anti-nausea drug response in children
Jan. 10, 2023—Genetic variation in a metabolic enzyme was not associated with response to the anti-nausea drug odansetron in children, Vanderbilt researchers report.
Study shows gene-drug interactions are common
Sep. 2, 2021—When a drug or combination of drugs causes different responses in different people, genetic variation is often at play. Pharmacogenomics, through discovery of genetic risk and use of clinical genotyping, aims to reduce trial-and-error approaches to drug prescribing.
Codeine metabolizer status in clinical practice
Apr. 5, 2021—Vanderbilt researchers have developed a response score using genetic and clinical information to aid prescribing of the widely used pain medication codeine.
PREDICT program expands, opens new Genomics Clinic
Apr. 30, 2020—A new clinic opening at Vanderbilt University Medical Center will help doctors and patients choose the best drugs for their medical conditions based on the patients’ unique genetic makeup.
Tailoring treatment for heart defect
Sep. 23, 2019—By defining the clinical and genetic factors that predict treatment response, Vanderbilt investigators aim to personalize therapy for a common heart complication in preterm infants.
Collaboration seeks to develop new therapies for bone, other diseases
Oct. 1, 2015—La Jolla Pharmaceutical Co. and Vanderbilt University have signed a research and license agreement covering Vanderbilt’s research program and intellectual property rights related to compounds that block bone morphogenetic protein (BMP) type-I receptors. The compounds have therapeutic potential in a broad range of diseases, including rare genetic disorders.
VUMC lands major pharmacogenomics grant
Jul. 9, 2015—Vanderbilt University Medical Center has received a five-year, $12.8 million grant from the federal government to develop better ways to predict how patients will respond to the drugs they’re given.
Lecture explores efforts to move pharmacogenetics into the clinic
Apr. 23, 2015—Preemptive genotyping: It sounds like a surprise attack, and it is.
Day of events to explore personalized medicine
Apr. 23, 2015—Vanderbilt faculty and staff are invited to attend Personalized Medicine Day on Friday, May 1, 8 a.m. to 4 p.m. at the Vanderbilt University Student Life Center.
Roden named to NIH’s genomics advisory council
Jun. 12, 2014—Dan Roden, M.D., assistant vice chancellor for Personalized Medicine, has been appointed to the National Advisory Council for Human Genome Research of the National Institutes of Health (NIH).
Eskind project seeks to demystify genotyping information for patients
Oct. 24, 2013—With the aid of a two-year, $487,000 National Leadership Grant from the Institute of Museum and Library Services (IMLS), a Vanderbilt research team will develop a reusable model to promote better patient engagement with the health care team through delivery of consumer-friendly pharmacogenetic information.
Pharmacogenomic testing costs studied
Oct. 17, 2013—A research team led by Josh Peterson, M.D., MPH, assistant professor of Biomedical Informatics and Medicine, and John Graves, Ph.D., assistant professor of Preventive Medicine, will study the cost-effectiveness of testing patients’ risk of adverse gene-drug interactions.
