Plos ONE Archives
Study proves standardized protocol can support reliable MRI use for multisite pancreatic research
Aug. 27, 2021—Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) at Vanderbilt University Medical Center led a multisite study which has demonstrated that, when controlled and standardized, quantitative magnetic resonance imaging (MRI) of the pancreas is highly reproducible when using different MRI hardware and software at different geographic locations.
Imaging “biomarker” for Alzheimer’s disease progression
Nov. 16, 2020—Changes in connectivity in the brain’s white matter may be a novel neuroimaging biomarker for assessing Alzheimer’s disease progression.
HIV prevention medication not being prescribed routinely: study
Sep. 17, 2020—Only about 54% of medical practitioners surveyed say they have prescribed pre-exposure prophylaxis, or PrEP, to HIV-vulnerable patients, according to a new study by a Vanderbilt University Medical Center investigator.
Race, hormones and diabetes risk
Mar. 19, 2020—Variation in the levels of hormones called natriuretic peptides may contribute to racial differences in susceptibility to diabetes, suggesting that this hormone system may be a target for reducing risk of the disease.
Intestinal immune cell interactions
Jul. 30, 2019—Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases.
A critical factor for wound healing
Jul. 16, 2019—Vanderbilt-Ingram Cancer Center scientists have discovered a role for a tumor suppressor protein in skin wound healing.
Pathways of radiosensitization
Apr. 11, 2019—Austin Kirschner and colleagues demonstrate how a hormone therapy for prostate cancer improves radiation’s tumor-killing power.
The arrestin-GPCR connection
Apr. 11, 2019—Understanding details of how arrestins deactivate signaling by G-protein coupled receptors is key to the design of new therapeutics aimed at these cellular "inboxes" that are targeted by up to half of all pharmaceuticals.
Community-driven health efforts saving lives in Lwala
Oct. 11, 2018—Eleven years after two Vanderbilt University medical students established a health care organization in an impoverished area of Kenya, the death rate for children under 5 years old has been cut in half, according to researchers from Kenya and the Vanderbilt Institute for Global Health (VIGH).
Mother knows best
Jul. 2, 2018—The first demonstration of bacterial DNA in mammalian fetal intestinal tissue suggests that the mother’s microbiome moves into the fetal intestine.
New method to thwart false positives in CT-lung cancer screening
May. 24, 2018—A team of investigators led by Fabien Maldonado, MD, associate professor of Medicine at Vanderbilt, and Tobias Peikert, MD, assistant professor of Medicine at Mayo Clinic, Rochester, Minnesota, has identified a new technology to address false positives in CT-based lung cancer screening. The study was published in the latest issue of PLOS One.
Number of minority trainees on rise, but not minority faculty
Jan. 25, 2018—Vanderbilt investigators examined the entire training pathway of potential biomedical research faculty and found two key points of loss: during undergraduate education and in transition from postdoctoral fellowship to tenure-track faculty.
