PLOS ONE

Metabolic profiling of vision loss

A panel of metabolites – small molecules that are part of metabolic processes – that are unique to macular degeneration will shed light on the disease and aid diagnosis.

Probing intestinal immune cell roles

A new in vitro system will allow investigators to explore how immune system T cells develop specialized functions.

Tumor factor spurs blood vessel growth

A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.

Oxidative stress in autism

A biomarker for oxidative stress is elevated in patients with both autism spectrum disorder and gastrointestinal dysfunction, suggesting opportunities for individualized approaches to clinical care.

Nuclear shield against cell death

The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold.

Chemical causes kidney failure in mosquitoes: study

Researchers are targeting a possible new weapon in the fight against malaria, science that could also be applied in the fight against other devastating mosquito-borne illnesses, according to a Vanderbilt study published in PLOS ONE.

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