PLoS Pathogens Archives
Temperature, newts and a skin-eating fungus
Mar. 8, 2021—Salamanders are more sensitive to a skin-eating fungus at colder temperatures, pointing to locations of North America where pathogen invasion is most likely.
Key factors in HIV-1 replication
Feb. 8, 2021—HIV-1, the virus that causes AIDS, exploits inositol phosphates in T cells to aid its own assembly and maturation — suggesting that targeting inositol phosphate binding could inhibit HIV-1 replication.
Study’s findings may help eventually close the door on COVID-19
Jan. 28, 2021—Researchers at Vanderbilt University Medical Center and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles’ heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly head off future pandemics.
Antibodies eye Pacific Island “fever”
May. 14, 2020—Vanderbilt Vaccine Center team isolates monoclonal antibodies against Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months.
Antibody isolated at VUMC found to halt dengue virus
Jan. 23, 2020—Using part of an antibody isolated at Vanderbilt that “broadly neutralizes” the human dengue virus, biologists at the University of California San Diego and colleagues have disarmed the mosquito that transmits the disabling and potentially deadly tropical infection.
Hope for an RSV vaccine
Feb. 23, 2018—Newly discovered features in an RSV protein may be useful for rational structure-based vaccine design.
Bacterial secretion machinery: 3-D view
Dec. 11, 2014—New structural findings reveal how "gatekeeper" proteins participate in the secretion systems bacteria use to infect host cells.
Host sequesters zinc to control stomach bug
Nov. 21, 2014—Understanding how zinc and the host’s immune response control H. pylori’s cancer-causing potential could suggest new therapeutic strategies to reduce infection and cancer risk.
Anthrax bacteria’s signaling systems
Apr. 15, 2014—Vanderbilt researchers have identified a new signaling system that anthrax bacteria uses to infect its host.
‘Proofreader’ key to coronavirus growth
Sep. 12, 2013—A coronavirus protein is required for replication of the viral genome and may be a good treatment target for SARS and other diseases caused by coronaviruses.
Zinc: a new antibiotic target?
Jan. 17, 2013—It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc.