Skip to main content

PNAS Archives

Predictive models for gene regulation

Aug. 16, 2018—Using new computational approaches to understand the behavior of cells should aid efforts to predict how mutations affect cell function and how diseases respond to drug combinations.

Read more


Fueling the MATE transporter

Jul. 19, 2018—Vanderbilt researchers used spectroscopy to understand how a drug transporter pumps drugs out of cells, findings that are important for developing novel anti-cancer and anti-bacterial drugs that can overcome drug resistance.

Read more


Understanding HDL structure

May. 3, 2018—Structural features of newly formed HDL particles will help guide understanding of “good cholesterol” and its function.

Read more


Iron-sulfur “intersection”

Mar. 8, 2018—Vanderbilt researchers have discovered an unanticipated link between sulfur and iron balance, pointing to a genetic basis for iron-deficiency anemia.

Read more


Glaucoma study finds brain fights to preserve vision

Feb. 22, 2018—A team of researchers, led by David Calkins, PhD, vice chair and director of Research at the Vanderbilt Eye Institute, has made a breakthrough discovery in the field of glaucoma showing new hopes for treatments to preserve vision.

Read more


BOLD view of white matter

Jan. 12, 2018—Vanderbilt investigators have discovered that functional MRI detects neural activity in both gray and white matter in the brain, suggesting new ways to investigate diseases such as Alzheimer’s and multiple sclerosis.

Read more


Lighting up iron levels

Jan. 11, 2018—A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease.

Read more


Brain lesions and criminal behavior linked to moral decision-making network

Dec. 18, 2017—When brain lesions occur within the brain network responsible for morality and value-based decision-making, they can predispose a person toward criminal behavior, according to new research by Ryan Darby, MD, assistant professor of Neurology at Vanderbilt University Medical Center (VUMC).

Read more


An immune regulator of addiction

Aug. 4, 2017—Although drug addiction is classically studied in a neuron-centric way, Vanderbilt researchers have discovered that the immune system also plays a critical role.

Read more


HDAC3 role in B-cell development

Aug. 3, 2017—The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies.

Read more


Study finds common brain scanning technique maps electrical activity as precisely as more invasive methods

May. 25, 2017—A commonly used brain scanning technique can map electrical activity under the skull as precisely as more invasive methods that rely on probes or electrodes, researchers at Vanderbilt University Medical Center (VUMC) reported this month.

Read more


A new mode of DNA repair

Apr. 14, 2017—Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.

Read more


Recent Stories from VUMC News and Communications Publications

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer.  Don’t hesitate. Do it.

Momentum

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer. Don’t hesitate. Do it.

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

more