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PNAS Archives

Setting traps to probe gene function

Oct. 18, 2012—A new method for creating genetic mutations that can be activated at certain times or in specific tissues will enable studies to probe gene function.

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Receptor’s role in nutrition brain circuitry

Jul. 3, 2012—New findings point to brain circuitry that communicates about the body’s nutritional status and regulates how nutrients are mobilized.

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Dengue antibodies give vaccine leads

Apr. 27, 2012—New information may help speed development of a vaccine or treatment for dengue fever.

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‘Detangler’ binds, bends and cuts DNA

Mar. 2, 2012—New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents.

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Alcohol’s molecular mediators

Jan. 23, 2012—Therapeutic agents focusing on the brain region involved in stress-induced relapse may be effective in preventing relapse in patients with alcohol use disorders.

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Protein combos keep cells straight

Mar. 18, 2011—Researchers define the protein interactions that establish our organs' lining.

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