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pneumonia Archives

Enhancing innate immunity in the lung

Sep. 12, 2022—Vanderbilt researchers show that a TLR4 agonist improves lung immune response and survival in a mouse model of bacterial pneumonia, supporting the development of this drug to protect against pneumonia in hospitalized patients.

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Study finds shorter treatment better for young children with outpatient pneumonia

Feb. 3, 2022—A Vanderbilt study found that five days of antibiotics is superior to 10 days for children with community-acquired pneumonia who are not hospitalized.

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Study finds genetic clues to pneumonia risk and COVID-19 disparities

Jan. 21, 2021—Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences.

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Probing pathogen antibiotic resistance

Sep. 17, 2020—Understanding how bacteria evolve resistance to antibiotics and host stresses could guide the development of more effective antimicrobial therapeutics.

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Zinc uptake by a deadly pathogen

Jan. 13, 2020—The increasingly antibiotic-resistant bacterium Acinetobacter baumannii requires zinc to cause infection, and Vanderbilt researchers have identified the zinc uptake system it uses.

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Amoxicillin alone better choice for pediatric pneumonia: study

Nov. 9, 2017—A combination of two antibiotics is often prescribed to treat community-acquired pneumonia in children, but a JAMA Pediatrics study is now showing that using just one of the two has the same benefit to patients in most cases.

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Study tests shorter antibiotic course in children

Dec. 1, 2016—Researchers at Vanderbilt University Medical Center (VUMC) are leading a multicenter clinical trial to evaluate whether a shorter course of antibiotics — five days instead of 10 — is effective at treating community-acquired pneumonia (CAP) in children who show improvement after the first few days of taking antibiotics.

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A bundle, a dashboard and lasting pneumonia reduction

Oct. 20, 2015—A “bundle” of electronically implemented care guidelines reduced intensive care unit patient complications related to mechanical ventilation.

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Flu vaccine helps reduce hospitalizations due to influenza pneumonia: study

Oct. 6, 2015—More than half of hospitalizations due to influenza pneumonia could be prevented by influenza vaccination, according to a study led by investigators at Vanderbilt University Medical Center, published this week in the Journal of the American Medical Association.

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Study highlights pneumonia hospitalizations among U.S. adults

Jul. 15, 2015—Viruses, not bacteria, are the most commonly detected respiratory pathogens in U.S. adults hospitalized with pneumonia, according to a New England Journal of Medicine study released today and conducted by researchers at Centers for Disease Control and Prevention (CDC) and hospitals in Chicago and Nashville, including Vanderbilt University Medical Center.

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Vanderbilt-led multi-center study looks at antibiotic choice for treating childhood pneumonia

Jun. 22, 2015—New Vanderbilt-led research shows hospitals are doing a better job of using antibiotics less commonly associated with antibiotic resistance to treat children hospitalized with community-acquired pneumonia (CAP).

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Respiratory viruses are main childhood pneumonia culprit: Study

Feb. 26, 2015—Respiratory viruses, not bacterial infections, are the most commonly detected causes of community-acquired pneumonia in children, according to new research released Feb. 26 in the New England Journal of Medicine.

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