pneumonia Archives

Patient Mathias Uribe with his parents, Mathias Uribe and Catalina Gutierrez, and his younger brother, Nicholas.

Young patient’s recovery from infection, multiple amputations, moves to next phase

Nov. 21, 2023—After 143 days in the Pediatric Intensive Care Unit at Monroe Carell Jr. Children’s Hospital at Vanderbilt, Mathias Uribe was discharged to begin the next phase of his recovery following a lengthy infection that led to a rare sequence of health issues.

From left, Frank Harrell Jr., PhD, Paul Harris, PhD, Wesley Self, MD, James Chappell, MD, PhD, Gordon Bernard, MD, Jana Shirey-Rice, PhD, and Jillian Rhoads, PhD, play key roles in a national effort to advance the understanding and treatment of acute respiratory distress syndrome, pneumonia and sepsis.

VUMC to coordinate national effort to reduce ARDS, pneumonia, sepsis

May. 4, 2023—Vanderbilt University Medical Center has received a $31.6 million federal grant to lead a national effort to better understand acute respiratory distress syndrome, pneumonia and sepsis.

Andrew Wiese, MPH, PhD, left, Carlos Grijalva, MD, MPH, and colleagues found that the risk of a heart attack diagnosis was highest in the first week after onset of pneumococcal infection.

Serious pneumococcal infections increase the risk of heart attack

Mar. 2, 2023—A Vanderbilt study found that patients with serious pneumococcal infections, including pneumonia and sepsis, are at a substantially increased risk of heart attack after the onset of infection.

The study team included, from left, Linh Tran, Ruben Barricade, PhD, Jaren Perez, and Xin Zhen. (photo by Susan Urmy)

Study reveals new genetic disorder that causes susceptibility to opportunistic infections

Jan. 20, 2023—An international consortium co-led by Vanderbilt's Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia.

Enhancing innate immunity in the lung

Sep. 12, 2022—Vanderbilt researchers show that a TLR4 agonist improves lung immune response and survival in a mouse model of bacterial pneumonia, supporting the development of this drug to protect against pneumonia in hospitalized patients.

Study finds shorter treatment better for young children with outpatient pneumonia

Feb. 3, 2022—A Vanderbilt study found that five days of antibiotics is superior to 10 days for children with community-acquired pneumonia who are not hospitalized.

Study finds genetic clues to pneumonia risk and COVID-19 disparities

Jan. 21, 2021—Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences.

Probing pathogen antibiotic resistance

Sep. 17, 2020—Understanding how bacteria evolve resistance to antibiotics and host stresses could guide the development of more effective antimicrobial therapeutics.

Zinc uptake by a deadly pathogen

Jan. 13, 2020—The increasingly antibiotic-resistant bacterium Acinetobacter baumannii requires zinc to cause infection, and Vanderbilt researchers have identified the zinc uptake system it uses.

Amoxicillin alone better choice for pediatric pneumonia: study

Nov. 9, 2017—A combination of two antibiotics is often prescribed to treat community-acquired pneumonia in children, but a JAMA Pediatrics study is now showing that using just one of the two has the same benefit to patients in most cases.

Study tests shorter antibiotic course in children

Dec. 1, 2016—Researchers at Vanderbilt University Medical Center (VUMC) are leading a multicenter clinical trial to evaluate whether a shorter course of antibiotics — five days instead of 10 — is effective at treating community-acquired pneumonia (CAP) in children who show improvement after the first few days of taking antibiotics.

A bundle, a dashboard and lasting pneumonia reduction

Oct. 20, 2015—A “bundle” of electronically implemented care guidelines reduced intensive care unit patient complications related to mechanical ventilation.