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Polygenic Risk Score Archives

Genetics and blood pressure

May. 19, 2022—Including polygenic risk scores for blood pressure may improve predictive models to identify people at risk for treatment-resistant hypertension.

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Calculating risk for uterine fibroids

Apr. 26, 2022—Vanderbilt researchers have constructed a polygenic risk score for uterine fibroids that will be useful for exploring causes of these benign tumors and identifying novel drug targets and therapies.

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VUMC joins national effort to improve disease prediction in diverse populations

Jun. 16, 2021—Vanderbilt University Medical Center will participate in a new federal initiative aimed at improving the use of polygenic risk scores (PRS) to predict complex diseases in diverse populations.

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A step toward cancer prevention

Aug. 10, 2020—A computational technique that combines the effect of multiple genomic variants has the potential to identify high-risk individuals for cancer prevention.

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Polygenic scores identify those at high cancer risk

Apr. 23, 2020—A team of Vanderbilt researchers constructed polygenic risk scores (PRS) based on genomic variants associated with eight common cancers and concluded they could potentially be used for personalized risk assessments.

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Study finds certain genetic test not useful in predicting heart disease risk

Feb. 27, 2020—A Polygenic Risk Score — a genetic assessment that doctors have hoped could predict coronary heart disease (CHD) in patients — has been found not to be a useful predictive biomarker for disease risk.

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Recent Stories from VUMC News and Communications Publications

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