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Reporter Aug 31 2018

Unleashing TIGER on small RNAs

Sep. 5, 2018—Vanderbilt investigators have developed a new analytical tool to identify, quantify and analyze small RNAs.

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A brain-builder called “Shh”

Aug. 30, 2018—New findings demonstrate a previously unappreciated role of Shh signaling activity in the proliferation of CGNPs — the presumed cell-of-origin for a subset of the malignant pediatric brain tumor medulloblastoma.

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Energetic gene switch

Aug. 30, 2018—New findings link flux through glycolysis, which produces cellular energy, with transcription and gene expression via histone modification.

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Using light to fight GVHD

Aug. 30, 2018—Extracorporeal photopheresis treatment for stem cell transplant-related complications produces a response in up to 60 percent of patients.

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Major award seeks to improve stroke outcomes

Aug. 30, 2018—Vanderbilt’s Kenneth Gaines, MD, MBA, professor of Clinical Neurology, has received a $15.7 funding award to determine if stroke outcomes can be improved with a redesigned and better-integrated model of care.

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Parkinson’s study to track impact of DBS on earliest patients

Aug. 30, 2018—A decade after taking part in the first clinical trial of deep brain stimulation (DBS) administered during very early-stage Parkinson’s disease, participants will return to Vanderbilt University Medical Center this year to be re-evaluated.

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Thomas takes on two new leadership roles at Children’s Hospital

Aug. 30, 2018—John Thomas, MD, associate professor of Pediatric Urology, has two new roles at Monroe Carell Jr. Children’s Hospital at Vanderbilt. Thomas has assumed a newly created role as clinical director for the OR at Children’s Hospital and is an associate chief of staff.

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Study links aortic stiffness with lower cerebral blood flow

Aug. 30, 2018—Greater aortic stiffness is related to lower cerebral blood flow, especially among individuals with increased genetic predisposition to Alzheimer’s disease, according to research from Vanderbilt University Medical Center.

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The boys of summer

Aug. 30, 2018—Nashville Sounds baseball players recently spent time at Monroe Carell Jr. Children’s Hospital at Vanderbilt, where they played a game in Seacrest Studios and visited with patients and families.

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Gould awarded Sutherland Prize for Achievement in Research

Aug. 30, 2018—Vanderbilt University’s most prestigious faculty honor for accomplishments in research, scholarship or creative expression was awarded to Kathleen Gould, PhD, during the Fall Faculty Assembly Aug. 23.

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Team isolates antibodies that neutralize GI bug norovirus

Aug. 30, 2018—Researchers at Vanderbilt University Medical Center have isolated the first human monoclonal antibodies that can neutralize norovirus, the leading cause of acute gastrointestinal illness in the world.

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Investigators find that bile acids reduce cocaine reward

Aug. 30, 2018—Bile acids — gut compounds that aid in the digestion of dietary fats — reduce the desire for cocaine, according to a new study by researchers at Vanderbilt and the University of Alabama at Birmingham.

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