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Research Archives

Caught in a web: study reveals that immune cells cooperate to trap and kill bacteria

Sep. 10, 2021—Vanderbilt researchers have identified a new antibacterial mechanism that could inspire novel strategies for combating staph and other extracellular bacterial pathogens.

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Novel immunotherapy shows robust response for multiple myeloma

Sep. 10, 2021—Vanderbilt research found that a novel immunotherapy demonstrated robust effectiveness in treating relapsed or refractory multiple myeloma.

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VUMC antibodies help neutralize two deadly viruses: study

Sep. 8, 2021—Vanderbilt researchers have isolated monoclonal antibodies that prevent severe illness and death caused by two emerging and deadly viruses called Nipah and Hendra.

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Regulators of fat cell metabolism

Sep. 7, 2021—Vanderbilt researchers have discovered new details of the regulation of fat cell metabolism, findings that are important for combating obesity.

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Medical diagnoses in musicians

Sep. 6, 2021—Vanderbilt researchers mined electronic health records to find medical diagnoses that are more or less prevalent among musicians, who are present in large numbers in “Music City.”

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White matter and schizophrenia

Sep. 2, 2021—Patients with schizophrenia have functional changes in the white matter of the brain, Vanderbilt researchers have discovered, which may contribute to impaired working memory and processing speed.

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Using billing codes to count cancers

Sep. 2, 2021—The billing codes in electronic health records are useful for counting skin cancers over time — an important metric for cancer risk assessment and prevention.

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Rheumatoid arthritis drug combined with standard of care may help reduce mortality for hospitalized COVID-19 patients

Sep. 2, 2021—Hospitalized patients with COVID-19 who received the rheumatoid arthritis drug baricitinib, in combination with the standard of care including corticosteroids, died less often than those receiving only the standard of care, according to a study released this week in The Lancet Respiratory Medicine.

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Discovery offers insight for development of cancer therapies targeting mutant p53

Sep. 2, 2021—Vanderbilt researchers have discovered that aneuploidy (an abnormal number of chromosomes) drives malignant phenotypes in cells expressing mutant p53, a tumor suppressor protein that is mutated in more than half of all human cancers.

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Study shows gene-drug interactions are common

Sep. 2, 2021—When a drug or combination of drugs causes different responses in different people, genetic variation is often at play. Pharmacogenomics, through discovery of genetic risk and use of clinical genotyping, aims to reduce trial-and-error approaches to drug prescribing.

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Autoimmunity advance

Aug. 24, 2021—Vanderbilt researchers have developed a high-throughput screening method to identify and characterize antigen-specific B cells — potential biomarkers for autoimmune disease and targets for new treatments.

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Estrogen, depression and menopause

Aug. 23, 2021—A shift in emotional processing may help women adapt to lower estrogen after menopause —unless they have a history of major depressive disorder, Vanderbilt researchers have found.

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