Research Archives

James Crowe Jr., MD, and colleagues are exploring how the body’s immune system gears up to fight off infection.

Vanderbilt vaccine pioneer James Crowe honored with major science prize

Jul. 9, 2019—James Crowe Jr., MD, director of the Vanderbilt Vaccine Center, will be honored today by the science and technology company Merck KGaA, Darmstadt, Germany for his contributions to developing new therapeutics and vaccines against some of the world’s deadliest viruses.

Clinical study tests drug that may prevent cancer metastasis

Jul. 8, 2019—A clinical study of a drug that may block cancer metastasis is currently enrolling patients at the Vanderbilt-Ingram Cancer Center.

Former Pharmacology chair Hardman remembered as gifted scientist, educator, mentor

Jul. 2, 2019—Joel Hardman, PhD, an internationally recognized scientist and educator who chaired the Department of Pharmacology at Vanderbilt University School of Medicine from 1975 to 1990, died June 30, 2019 in Hoosick Falls, New York, after a lengthy illness. He was 85.

Benzodiazepine use with opioids intensifies neonatal abstinence syndrome

Jul. 1, 2019—Babies born after being exposed to both opioids and benzodiazepines before birth are more likely to have severe drug withdrawal, requiring medications like morphine for treatment, compared to infants exposed to opioids alone.

Biomarkers of DNA methylation can be a predictor of breast cancer risk

Jun. 26, 2019—Biomarkers of DNA methylation, which regulate gene expression, can be a predictor of breast cancer risk.

David Morrison, MD, and colleagues are studying whether to implant an artificial intraocular lens or fit a contact lens over a baby’s cornea after cataract surgery.

Study explores treatment options for babies with cataracts

Jun. 26, 2019—Cataracts are uncommon in babies but when they occur the cloudy lenses must be removed without delay or blindness may result.

ABIM Foundation honors VUMC-authored paper

Jun. 20, 2019—The ABIM Foundation has awarded the 2019 John A. Benson Jr., MD Professionalism Article Prize to five scholarly articles — one commentary and four research pieces — that explore physician burnout, unprofessional behavior and integrity in research.

Study identifies critical regulator of tumor-specific T cell differentiation

Jun. 18, 2019—A study published June 17 in Nature offers clues as to why blocking inhibitory receptors on tumor-infiltrating T cells may not always work

Cardiac toxicity risk factors identified with relapsed multiple myeloma therapy

Jun. 13, 2019—More than half of patients with relapsed multiple myeloma treated with carfilzomib experienced cardiac issues during treatment, according to a multi-institutional study published June 12 in the Journal of Clinical Oncology.

Eng named to GI cancer leadership position at VICC

Jun. 13, 2019—Cathy Eng, MD, a national and international leader in gastrointestinal medical oncology, is joining Vanderbilt-Ingram Cancer Center (VICC).

From left, Alexander Gelbard, MD, Suman Das, PhD, and Simon Mallal, MBBS, are among a team of researchers searching for the cause of a rare airway disease that almost exclusively affects adult, Caucasian women.

Study seeks to expand treatment options for rare airway disease

Jun. 13, 2019—Armed with $1.2 million in funding from the National Heart, Lung and Blood Institute (NHLBI), researchers at Vanderbilt University Medical Center are searching to understand the cause of a rare airway disease in hopes of developing better treatments.

Treatment approved for patients with acute graft-versus-host disease

Jun. 13, 2019—The U.S. Food and Drug Administration (FDA) recently approved ruxolitinib, the first drug for patients with acute graft-versus-host disease (GVHD) who have an inadequate response to steroid treatment. VUMC's Madan Jagasia, MBBS, MS, MMHC, was a lead investigator of the REACH1 trial that was the basis for the FDA approval.