Research Archives
Study finds similar success rates with two devices for breathing tube placement
Dec. 15, 2021—Two devices for placing a breathing tube during critical illness had similar success rates for intubation on the first attempt, according to a study published Dec. 8 in JAMA.
Study sets framework for precision surveillance of colorectal cancer
Dec. 14, 2021—Vanderbilt research has revealed some of the mechanisms by which polyps develop into colorectal cancer, setting the framework for improved surveillance for the cancer utilizing precision medicine.
Immune landscape in adrenal cancer
Dec. 14, 2021—The profile of immune-related gene expression and tumor-infiltrating immune cells in adrenocortical cancer suggests targets for new treatment strategies.
Oral microbes and gastric cancer
Dec. 13, 2021—Studies in three large population cohorts that include Asian, African American and European American people support a role for the oral microbiota — the collection of microbial species in the mouth — in gastric cancer development.
“Supermeres” may carry clues to cancer, Alzheimer’s disease and COVID-19
Dec. 10, 2021—Vanderbilt researchers have discovered a nanoparticle released from cells, called a “supermere,” which contains enzymes, proteins and RNA associated with multiple cancers, cardiovascular disease, Alzheimer’s disease and even COVID-19.
Cell signaling targets in leukemia
Dec. 9, 2021—Vanderbilt researchers identified a critical role for IL-1beta signaling in leukemia cells with a certain mutation, suggesting this pathway may be a good target for novel treatments.
Prostate cancer treatment regret
Dec. 9, 2021—Vanderbilt researchers suggest that to reduce treatment-related regret for men with localized prostate cancer, treatment preparation should focus on shared decision-making and aligning patient expectations with treatment toxicity.
International study supports dupilumab for treatment of moderate-to-severe asthma in children
Dec. 8, 2021—In a late-stage clinical trial, the biologic agent dupilumab reduced the rate of severe asthma attacks and improved lung function and asthma control for children ages 6 to 11 with moderate-to-severe asthma, offering a new option to these patients.
Gene discoveries give new hope to people who stutter
Dec. 2, 2021—New research shows the potential to identify therapeutic directions that could improve outcomes for people who stutter.
Long-acting antibody combo developed at VUMC reduces COVID-19 risk and symptoms
Dec. 2, 2021— by Bill Snyder The global biopharmaceutical company AstraZeneca announced more good news about its long-acting combination of two monoclonal antibodies against COVID-19 that were discovered at Vanderbilt University Medical Center. In a prevention trial, one prophylactic, intramuscular injection of the antibody combination, called AZD7442, reduced the risk of symptoms occurring after exposure to the...
Thyroid cancer paper lands national recognition
Dec. 2, 2021—by Tom Wilemon A group of investigators in the Endocrine Neoplasia Research Laboratory at Vanderbilt University Medical Center has received national recognition for their work to discover better treatments for thyroid cancer. A paper describing their lab work was awarded first place in the Basic Science category at the 2021 Cancer Research Competition, which promotes...
Study links depression scores, white blood cell count
Dec. 2, 2021— by Emily Stembridge Researchers across four health care systems, including Vanderbilt University Medical Center, have found that increased depression polygenic scores are associated with increased white blood cell count, highlighting the importance of the immune system in the etiology of depression. Despite a wide understanding of depression as a psychiatric disorder, depression’s underlying biological...
