Research Archives
International study supports dupilumab for treatment of moderate-to-severe asthma in children
Dec. 8, 2021—In a late-stage clinical trial, the biologic agent dupilumab reduced the rate of severe asthma attacks and improved lung function and asthma control for children ages 6 to 11 with moderate-to-severe asthma, offering a new option to these patients.
Gene discoveries give new hope to people who stutter
Dec. 2, 2021—New research shows the potential to identify therapeutic directions that could improve outcomes for people who stutter.
Long-acting antibody combo developed at VUMC reduces COVID-19 risk and symptoms
Dec. 2, 2021— by Bill Snyder The global biopharmaceutical company AstraZeneca announced more good news about its long-acting combination of two monoclonal antibodies against COVID-19 that were discovered at Vanderbilt University Medical Center. In a prevention trial, one prophylactic, intramuscular injection of the antibody combination, called AZD7442, reduced the risk of symptoms occurring after exposure to the...
Thyroid cancer paper lands national recognition
Dec. 2, 2021—by Tom Wilemon A group of investigators in the Endocrine Neoplasia Research Laboratory at Vanderbilt University Medical Center has received national recognition for their work to discover better treatments for thyroid cancer. A paper describing their lab work was awarded first place in the Basic Science category at the 2021 Cancer Research Competition, which promotes...
Study links depression scores, white blood cell count
Dec. 2, 2021— by Emily Stembridge Researchers across four health care systems, including Vanderbilt University Medical Center, have found that increased depression polygenic scores are associated with increased white blood cell count, highlighting the importance of the immune system in the etiology of depression. Despite a wide understanding of depression as a psychiatric disorder, depression’s underlying biological...
Study provides new insight into how antidepressant drugs work
Dec. 1, 2021—A study by Vanderbilt researchers sheds light on how current antidepressant drugs work and suggests a new drug target in depression.
‘Multi-omics’ reveals treatment option for breast cancer subtype
Nov. 18, 2021— by Bill Snyder In a multidisciplinary collaboration, researchers at Vanderbilt University Medical Center and the University of Miami Miller School of Medicine have identified a subtype of triple-negative breast cancer (TNBC) that appears to be able to escape detection by the immune system and evade immunotherapy. Their report, published Nov. 1 in the journal...
Seven from VUMC among most highly cited researchers
Nov. 18, 2021—Seven Vanderbilt faculty members have made this year’s list of scientists whose papers have been cited most frequently by other researchers.
AI predicts 24-hour hospital discharge
Nov. 16, 2021—Vanderbilt researchers used a machine learning algorithm and data from more than 26,000 hospital stays to predict who would and would not be discharged over the next 24 hours.
Who’s who in the respiratory landscape
Nov. 15, 2021—A metatranscriptomics method developed by Vanderbilt researchers simultaneously characterizes viruses, microbiome and host response in nasal swabs, opening opportunities to explore molecular interactions directly in clinical samples.
CRISPR screen identifies new anti-inflammatory drug target
Nov. 11, 2021—A novel CRISPR screen developed by Vanderbilt researchers identified a promising new target for anti-inflammatory therapeutics.
The power of white matter
Nov. 11, 2021—Using a novel analysis of fMRI data, Vanderbilt researchers discovered intriguing patterns of signals in the brain’s white matter, the “conduit” for relaying signals between different brain regions.
