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Research Archives

Mosaicism and genetic disease

Jun. 22, 2023—Genetic mosaicism — when the body’s cells do not all have the same genetic makeup — could generate variants previously thought to be spontaneous in genetic disease, and detecting parental mosaicism could clarify recurrence risk for future children.

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VUMC, Oxford team develops ‘blueprint’ to block lethal virus

Jun. 22, 2023—Researchers at Vanderbilt University Medical Center and the University of Oxford have determined how a human monoclonal antibody isolated at Vanderbilt in 2021 can prevent infection by the potentially lethal Sin Nombre virus.

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Vanderbilt launches $17 million program to advance diversity of research faculty

Jun. 21, 2023—Vanderbilt University Medical Center and Vanderbilt University are launching a $17 million multiyear transformative program with support from the National Institutes of Health to accelerate diversity, equity, inclusion and belonging in the biomedical research community.

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Early-onset CRC germline genetic differences identified by race, ethnicity

Jun. 15, 2023—A Vanderbilt study that delved into genetic predisposition for early-onset colorectal cancer by race and ethnicity has identified differing germline risk variants.

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NIH grant boosts international TB research consortium

Jun. 14, 2023—A new grant will help support Vanderbilt's RePORT Brazil, one of an international consortium’s six regional tuberculosis research programs.

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Maternal diet influences postnatal diabetes risk

Jun. 13, 2023—Studies in a primate animal model suggest that islet hyperfunction — which in humans is associated with increased fat mass and Type 2 diabetes — is programmed in offspring by a maternal Western-style diet during pregnancy.

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Images predict functional decline

Jun. 12, 2023—MRI brain scans at baseline for study participants 60 and older — who were free of clinical dementia at study entry — predicted a decline in independent function five years later.

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Targeting calcium handling in A-fib

Jun. 8, 2023—The drug ent-verticilide reduced A-fib incidence and duration in an animal model, suggesting it may be a viable therapeutic option.

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An image of cancer treatment response

Jun. 8, 2023—An MRI method developed by Vanderbilt researchers uses imaging data to derive cell size and could be added to clinical practice for better monitoring of breast cancer treatment response.

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Enhanced treatment helps fast nicotine metabolizers quit smoking

Jun. 8, 2023—A study from Vanderbilt researchers has found that enhanced treatment support can help smokers who have more difficulty quitting because they are fast metabolizers of nicotine.

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Byndloss selected for Burroughs Wellcome Fund infectious disease award

Jun. 7, 2023—Vanderbilt's Mariana Byndloss, DVM, PhD, is one of eight Burroughs Wellcome Fund 2023 Investigators in the Pathogenesis of Infectious Disease.

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Treating kidney injury before it happens

May. 23, 2023—Pretreatment of an animal model with a novel compound called PHAD reduced kidney injury, suggesting it may be a good candidate for preventing kidney injury in surgical patients.

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