Oct. 21, 2021—An international research team has developed a new resource that connects genetic variants and protein expression, which is expected to speed the identification of genes that cause disease — and point to novel treatment strategies.
Aug. 12, 2021—A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.
Jul. 9, 2020—Mariana Byndloss, DVM, PhD, assistant professor of Pathology, Microbiology and Immunology, has been selected as a runner-up of the inaugural NOSTER & Science Microbiome Prize.
Dec. 5, 2019—Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions.
May. 29, 2019—P-glycoprotein distinguishes between chemicals that it will expel from a cell and inhibitors that block its action.
Mar. 7, 2019—The release of neurotransmitters and hormones in the body is tightly controlled by complex protein machinery embedded in cell membranes.
Vanderbilt experts discuss potential of universal genetic database to balance privacy, law enforcement concerns
Jan. 3, 2019—The pivotal role that long distance familial genetic searches played in the apprehension of the notorious Golden State Killer — and as a tool in dozens more cases since — has led experts from Vanderbilt University and Vanderbilt University Medical Center to make a provocative proposal about how investigative use of DNA should be regulated.
Feb. 23, 2017—DNA replication is an extraordinarily complex multi-step process that makes copies of the body’s genetic blueprint. It is necessary for growth and essential to life. Now researchers at the California Institute of Technology (Caltech) and Vanderbilt University have found evidence that one of those steps may involve the telephone-like transmission of electrical signals regulated by a chemical “switch.”
Sep. 8, 2016—A multi-center research team including scientists from the Vanderbilt Vaccine Center has come up with a clever “Trojan Horse” strategy for thwarting the highly lethal Ebola virus.
Aug. 11, 2016—Terunaga Nakagawa, with colleagues from Japan and Oxford University in England, has discovered the bridgelike molecular structure of a mysterious glutamate receptor.