Scientific Reports Archives
Acid reflux cancer link
Sep. 14, 2017—Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer.
Esophageal cancer complexities
Mar. 16, 2017—New findings that reveal complex interactions in esophageal adenocarcinoma could lead to diagnostic, prognostic or therapeutic biomarkers.
Melanoma study finds new way to enhance targeted therapies
Mar. 9, 2017—With the help of a drug formerly used to treat HIV/AIDS, researchers at Vanderbilt University Medical Center (VUMC) have found a way to make melanoma cells more vulnerable to targeted anti-cancer therapy.
Improving vaccine formulations
Jan. 20, 2017—The compound MPLA is an attractive vaccine component, designed to elicit a robust immune response.
Investigators explore new way to control mosquitoes
Dec. 1, 2016—In a new study, Vanderbilt pharmacologist Jerod Denton, Ph.D., Ohio State entomologist Peter Piermarini, Ph.D., and colleagues report an experimental molecule that inhibits kidney function in mosquitoes and thus might provide a new way to control the deadliest animal on Earth.
Protein structure and epilepsy severity
Nov. 10, 2016—Understanding how mutations affect the structure and function of inhibitory neurotransmitter receptors will shed light on the mechanisms underlying some types of epilepsy.
Pulmonary fibrosis culprits
Jun. 6, 2016—New findings identify isoketal-modified proteins as a previously unrecognized feature of pulmonary fibrosis and as a potential therapeutic target for this disease.
New targets for diabetic retinopathy
Jan. 21, 2016—Certain protein factors have been identified as attractive targets for treating diabetic retinopathy, a major cause of blindness in adults.
‘Stretched’ cells promote cancer
Feb. 19, 2015—Mechanical stress appears to be a critical factor in activating normal tissue-associated fibroblasts to generate cancer-associated fibroblasts.
New tools to probe manganese biology
Nov. 26, 2014—Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.
