seizures Archives
VUMC implants first patient in NAUTILUS study for treatment of idiopathic generalized epilepsy
Oct. 18, 2022—A Vanderbilt patient with idiopathic generalized epilepsy is now the first to receive neuromodular stimulation of the brain to see if it can help with seizures.
Sudden death from deep in the brain?
Aug. 9, 2021—Vanderbilt neurologists found altered excitability in deep brain structures that they note may drive respiratory dysfunction and sudden death in a rare form of epilepsy.
Functional seizures associated with stroke, psychiatric disorders in electronic health records study
Jan. 7, 2021—In a large-scale study of electronic health records, Vanderbilt University Medical Center investigators have determined the prevalence of functional seizures and characterized comorbidities associated with them.
Single mutation causes seizure disorder
Jun. 22, 2020—A single mutation in one gene can impair inhibitory signaling in the brain and cause multiple types of seizures and behavioral abnormalities.
A new anti-seizure target?
Dec. 12, 2019—Vanderbilt neurologists have identified a protein modification that could be targeted to reduce neuronal excitability in epilepsy.
Study reveals mysteries of critical brain receptor complex
Dec. 5, 2019—Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions.
ROSA technology helps ease patient’s violent seizures
Dec. 5, 2019—In the span of a month in December 2018, Daniel Lookabaugh suffered six severe seizures, requiring hospitalization at Monroe Carell Jr. Children’s Hospital at Vanderbilt each time to have neurological care as well as intervention from Pediatric Orthopaedics to reset his jaw and shoulder.
Blueprint for treating epilepsy
Nov. 14, 2019—Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders.
Team discovers one more piece to the autism puzzle
Oct. 3, 2019—Vanderbilt investigators have linked genetic mutations in a single receptor to epilepsy, autism and intellectual disability.
Astrocytes and epilepsy
Sep. 9, 2019—A protein with important functions in astrocytes — star-shaped brain support cells — may alter neuronal excitability and contribute to seizure activity, Vanderbilt researchers report.
Brain network activity can improve in epilepsy patients after surgery
May. 16, 2019—Successful epilepsy surgery can improve brain connectivity like patterns seen in people without epilepsy, according to a new study.
Vitamin C protects brain from seizures
Nov. 8, 2018—Brain ascorbate — vitamin C — is important for protecting the brain against seizures and cognitive decline in Alzheimer’s disease.
