Dec. 5, 2019—Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions.
Dec. 5, 2019—In the span of a month in December 2018, Daniel Lookabaugh suffered six severe seizures, requiring hospitalization at Monroe Carell Jr. Children’s Hospital at Vanderbilt each time to have neurological care as well as intervention from Pediatric Orthopaedics to reset his jaw and shoulder.
Oct. 3, 2019—Vanderbilt investigators have linked genetic mutations in a single receptor to epilepsy, autism and intellectual disability.
May. 16, 2019—Successful epilepsy surgery can improve brain connectivity like patterns seen in people without epilepsy, according to a new study.