statins Archives
Probing statin-associated diseases with genetics
Jul. 12, 2021—Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.
Statins to be studied for prevention of dementia, disability and heart disease
Nov. 17, 2020—Vanderbilt University Medical Center (VUMC) researchers are enrolling adults aged 75 and over to study whether taking atorvastatin, a drug commonly used to lower cholesterol also called Lipitor®, can help maintain health by preventing dementia, disability, and heart disease.
Records point to drug-drug interaction
May. 7, 2018—Patients who take a cholesterol-lowering statin drug while taking the antibiotic daptomycin have increased risk of developing muscle weakness or a more severe form of muscle damage.
Gene study spots clues to heart risk for statin patients
May. 3, 2018—A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.
HDL and kidney injury after surgery
Jan. 17, 2018—Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered.
VUMC study finds statins do not ease kidney injury following cardiac surgery
Feb. 23, 2016—Among doctors, it is widely believed that a class of drugs called statins, which are used to lower cholesterol, might help patients tolerate the stress of cardiac surgery. Not so, according to a five-year, placebo-controlled, double-blinded randomized clinical trial conducted at Vanderbilt University Medical Center, published today in the Journal of the American Medical Association....
Study shows statin use improves renal cell cancer survival
Apr. 16, 2015—A new study led by Vanderbilt University investigators found that patients being treated with statins at the time of surgery for kidney cancer, also known as renal cell carcinoma, had improved overall survival and disease-specific survival.
E-records shed light on drug response
Mar. 31, 2014—Electronic medical records linked to DNA biobanks are a valid resource for defining and understanding the genetic factors that contribute to drug response.
PREDICT helps pinpoint right statin for patient
Oct. 4, 2012—When O.T. Hayes, 67, of Lebanon, Tenn., first starting seeing his cardiologist, David Hansen, M.D., for treatment of his coronary artery disease, it was hard to predict which of the various medications available would help control Haynes’ high cholesterol.
Vanderbilt doctors to screen patients taking statins for genetic risk factors
Oct. 28, 2011—Vanderbilt University Medical Center doctors announced today they will begin screening patients who take commonly prescribed statin drugs for a rare genetic variation that can increase risks for side effects from these drugs such as muscle aches, kidney damage and even death.
