stem cells Archives
Motor protein linked to intestinal cell differentiation
Aug. 5, 2021—The motor protein MYO5B, a cause of the congenital intestinal disorder microvillus inclusion disease, does more than move cellular cargo, Vanderbilt researchers have discovered.
Reprogramming cells for kidney repair
Mar. 14, 2019—Using gene transfer technologies to reprogram adult human kidney cells could lead to novel therapies for chronic kidney disease.
Structure of a stem cell niche
Feb. 28, 2018—Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies.
Stem cells promote tolerance
Nov. 17, 2016—Blood-forming stem cells play a role in immune tolerance and acceptance of organ transplants, Vanderbilt researchers have discovered.
Proliferative capacity of neuroblastoma
Aug. 31, 2016—The sphere-forming frequency of neuroblastoma cells is a measure of their proliferative capacity and could help guide treatment strategies for neuroblastoma.
Hhex on cancer
Jul. 13, 2015—A new mouse model demonstrates that the Hhex gene – which is linked to blood cancers – is critical for normal blood cell production.
Delivering cells for heart repair
Jul. 10, 2015—A polymer hydrogel material developed by Vanderbilt scientists improved the delivery of stem cells for heart repair.
Boosting cell-based heart repair
May. 15, 2015—A metabolic change in adult stem cells makes them less “fit” for regenerative heart therapies, suggesting that strategies to prevent this response may boost the therapeutic usefulness of the cells.
Long-range signaling to stem cells
Oct. 9, 2014—The potential for long-range signaling factors – such as those identified in the current study – to regulate stem cell behaviors has implications in tumor progression and metastasis.
Patient-derived stem cells shed light on pulmonary hypertension
Sep. 16, 2014—Stem cells derived from patients with pulmonary arterial hypertension provide a unique resource for studying the molecular defects that cause the disease and testing potential therapies.
Engelhardt lands stem cell transplant research grant
Sep. 11, 2014—Up to 60 percent of patients who receive a stem cell transplant using cells from another donor will develop post-transplant diabetes mellitus, which can increase the rate of complications and death after the procedure.
Study finds coronary arteries hold heart-regenerating cells
Aug. 20, 2014—Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, Vanderbilt University investigators have discovered.
