Susan G. Komen Foundation Archives
Surgery for hereditary breast cancer
Nov. 17, 2022—Similar rates of bilateral mastectomy in women with inherited mutations in high- and moderate-penetrance genes raises concerns about possible overtreatment of some patients, Vanderbilt researchers report.
Breast cancer biomarkers of response
Jun. 16, 2022—Vanderbilt researchers have identified blood-based biomarkers associated with complete responses to neoadjuvant chemotherapy in patients with breast cancer.
Probing cancer cell invasion
Mar. 1, 2022—The rigidity of the extracellular matrix that surrounds cells impacts the contractile and invasive properties of head and neck cancer cells.
Susan G. Komen funds VICC breast cancer initiatives
Jul. 15, 2021—Susan G. Komen has announced breast cancer research grants totaling $14 million, including funding for three separate initiatives led by Vanderbilt-Ingram Cancer Center (VICC) researchers.
Tuya Pal named Komen Scholar
Jun. 24, 2021—Susan G. Komen announced on June 23 that Tuya Pal, MD, associate director for Cancer Health Disparities at Vanderbilt-Ingram Cancer Center (VICC) and Ingram Professor of Cancer Research, has been named a Komen Scholar.
Breast cancer cells ‘steal’ nutrients from immune cells: study
Apr. 1, 2021—Triple-negative breast cancer cells engage in a “glutamine steal” — outcompeting T cells for the nutrient glutamine and impairing their ability to kill tumor cells, Vanderbilt researchers have discovered.
Triple-negative breast cancer drug therapy shows promise
Mar. 12, 2020—Researchers from Vanderbilt-Ingram Cancer Center (VICC) discovered a role for MYCN in triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, and identified a potential intervention for further clinical investigation.
Pietenpol, Wilson land Komen cancer research support
Oct. 24, 2019—Two Vanderbilt-Ingram Cancer Center investigators have received financial support from Susan G. Komen for breast cancer research.
A catalog of DNA replication proteins
Oct. 3, 2019—Vanderbilt scientists have identified 593 proteins that are enriched at sites of DNA duplication and chromatin packaging of newly synthesized DNA.
Achilles’ heel for kidney cancer
Feb. 28, 2019—The discovery that kidney cells with mutations in a certain gene are sensitive to therapies called PI3K inhibitors opens new opportunities for applying precision medicine to cancer treatment.
Novel DNA repair mechanism preserves genome integrity: study
Feb. 28, 2019—Biochemistry investigators at Vanderbilt have discovered a new DNA repair mechanism that prevents gene mutations during DNA replication.
Cancer Center investigators awarded Komen grants
Oct. 11, 2018—Four Vanderbilt-Ingram Cancer Center (VICC) investigators have received financial support from Susan G. Komen for breast cancer research.