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type 1 diabetes Archives

Trial participant steps up to help advance diabetes research

Sep. 1, 2022—Vanderbilt is one of 16 North American sites conducting the Tolerance Using Plasmid in People with Type 1 Diabetes (TOPPLE) study, a phase 1 investigation that tests the safety and dosing of a new plasmid therapy.

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International gathering scrutinizes immune response, beta cell biology in Type 1 diabetes

Nov. 11, 2021—  by Jill Clendening Nearly 400 investigators and scientific trainees hailing from 25 different countries recently gathered virtually, across continents and time zones, to share their latest research related to the immunology of Type 1 diabetes during the 18th Immunology of Diabetes Society (IDS) Congress, co-hosted by Vanderbilt University Medical Center and the University of...

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Autoimmunity advance

Aug. 24, 2021—Vanderbilt researchers have developed a high-throughput screening method to identify and characterize antigen-specific B cells — potential biomarkers for autoimmune disease and targets for new treatments.

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Gene expression in diabetic nephropathy

Aug. 5, 2021—Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease.

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Targeting glucagon action in diabetes

Mar. 4, 2021—Disrupting the action of glucagon — a pancreatic hormone that works to raise blood glucose — restores functional insulin-producing cells in mouse models of type 1 diabetes and may be a promising treatment strategy.

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Discovery may point to better treatments for Type 1 diabetes

Aug. 22, 2019—Researchers have made a paradigm-shifting discovery that could lead to new treatments, better health and longer life for patients with Type 1 diabetes.

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Study drug delays type 1 diabetes in high risk children and adults

Jun. 9, 2019—Drug delays onset of type 1 diabetes by two years

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Healthy antibodies reverse diabetes

Sep. 13, 2018—Vanderbilt researchers have discovered that IgM-type antibodies appear to play a protective role to prevent the development of type 1 diabetes — and that purified IgM antibodies can reverse the disease.

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Discovery by Vanderbilt-led group could lead to improved diabetes treatment

Mar. 6, 2018—Vanderbilt investigators and colleagues around the country have made a major discovery that could lead to better ways to treat type 1 diabetes (T1D).

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Study uses child’s own immune system against type one diabetes

Jun. 22, 2017—Eighteen-year-old Grace Long had just been accepted at the renowned United States Naval Academy, with plans to become a nuclear engineering officer. Then, she learned she had type 1 diabetes, an immediate disqualifier for military service.

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