Vanderbilt Center for Structural Biology Archives
NIH grant launches C. diff vaccine research initiative
Mar. 30, 2023—Vanderbilt has received an NIH grant to launch the Vanderbilt Antibody and Antigen Discovery for Clostridioides difficile Vaccines, or VANDy-CdV.
UT Southwestern’s Rosen up next in Discovery Lecture Series
Dec. 22, 2020—Michael Rosen, PhD, professor and chair of Biophysics at the University of Texas Southwestern Medical Center, will discuss mysterious cellular compartments known as “biomolecular condensates” during the next web-based Discovery Lecture.
A key to calcium signaling
Feb. 11, 2020—Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles.
Team’s study reveals details of new DNA repair pathway
Jul. 25, 2019—Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity.
Study details regulation of a multi-drug transporter
May. 29, 2019—P-glycoprotein distinguishes between chemicals that it will expel from a cell and inhibitors that block its action.
DNA’s on/off switch
Jan. 17, 2019—DNA-binding “switches” represent a fundamentally new method of communication between DNA-processing enzymes, Vanderbilt researchers propose.
New view of the heartbeat
Apr. 6, 2018—Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias.
Noted neuroscientist Gouaux set for Discovery Lecture
Feb. 15, 2018—Eric Gouaux, PhD, whose work has helped reveal the molecular mechanisms by which nerve cells communicate, will deliver the next Flexner Discovery Lecture Thursday, Feb. 22.
DNA damage repair: molecular insights
Dec. 5, 2017—Structural details about a protein involved in the repair of damaged DNA provide insight into xeroderma pigmentosum disorders, which are characterized by increased risk for skin cancer.
Repriming replication roadblocks
Jun. 12, 2017—New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.
A new mode of DNA repair
Apr. 14, 2017—Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.
Symposium on Modeling Immunity set for April 27
Apr. 5, 2017—The Vanderbilt Center for Structural Biology and the Vanderbilt Vaccine Center invite you to attend the 2017 Symposium on Modeling Immunity April 27. The event will focus on modeling and designing antibodies.