Vanderbilt Center for Structural Biology Archives
Repair protein’s DNA recognition motif
May. 23, 2014—Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer.
Bypassing DNA damage
May. 9, 2014—Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage.
Dismantling staph’s drug resistance
Mar. 3, 2014—Targeting the enzyme FosB could make antibiotic-resistant staph bacteria sensitive to the antibiotic fosfomycin.
Grad students help achieve key discovery
Oct. 24, 2013—A multidisciplinary study conducted by the combined efforts of Vanderbilt University graduate students has led to the first evidence that abnormal messenger RNA export from the nucleus to the cytoplasm can cause human disease.
Controversial info release aids VUMC bird flu research
Sep. 5, 2013—Vanderbilt research shows that human antibodies to the natural strain of H5N1 also protected against a dangerous lab-created airborne strain developed several years ago by scientists in the Netherlands and at the University of Wisconsin.
Protein Society honors Sanders
Feb. 28, 2013—Charles Sanders, Ph.D., professor of Biochemistry, has been selected as a recipient of the 2013 Hans Neurath Award from the Protein Society. He shares the honor with Jennifer Doudna, Ph.D., a Howard Hughes Medical Institute investigator at the University of California, Berkeley.
Antibacterial protein’s molecular workings revealed
Feb. 21, 2013—Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require.
Study tracks genes involved in heart rhythm disorders
Feb. 7, 2013—A team led by Vanderbilt University investigators has discovered two new genes — both coding for the signaling protein calmodulin — associated with severe early-onset disorders of heart rhythm.
New view of DNA processing ‘hub’
Jan. 23, 2013—Structural studies reveal a new framework for understanding a central player in DNA processing.
Seeing light receptor’s interactions
Jan. 18, 2013—Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development.
Zinc: a new antibiotic target?
Jan. 17, 2013—It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc.
