Vanderbilt Institute for Infection Immunology and Inflammation Archives
Study details RNA editing in virus-infected cancer cells
Apr. 20, 2023—Vanderbilt researchers detail the landscape of RNA editing — a form of RNA modification — in primary effusion lymphoma cells during Kaposi’s sarcoma-associated herpesvirus infection and identify an edited viral microRNA that is critical for infection.
NIH grant launches C. diff vaccine research initiative
Mar. 30, 2023—Vanderbilt has received an NIH grant to launch the Vanderbilt Antibody and Antigen Discovery for Clostridioides difficile Vaccines, or VANDy-CdV.
Mathers Foundation award supports study of bacterial physiology
Mar. 23, 2023—Vanderbilt's Wenhan Zhu, PhD, has received a three-year award from the G. Harold and Leila Y. Mathers Foundation to support his research that aims to answer a fundamental question about bacterial physiology and engineer probiotics to improve gut inflammatory diseases.
E. coli uses serine to abide acidity
Mar. 23, 2023—Vanderbilt researchers have discovered another acid resistance mechanism for UTI-causing E. coli, laying the foundation for targeted antibacterial therapies.
Probing hellbender health
Feb. 20, 2023—Understanding how hellbenders — large, fully aquatic salamanders — fight fungal pathogens and disease is important for protecting these unique stream predators; Vanderbilt researchers add new insights.
Study identifies potential new approach for treating lupus
Jan. 13, 2023—A Vanderbilt study found that targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus — the most common form of the chronic autoimmune disease lupus.
VUMC lands grant to build top-line biosafety facility
Sep. 29, 2022—Vanderbilt University Medical Center is set to construct a state-of-the-art BioSafety Level 3 (BSL3) facility for research involving the COVID-19 virus, anthrax and other dangerous microorganisms.
MEGAMicrobe event shows children that science can be fun
Sep. 22, 2022—More than 100 children who attended the “MEGAMicrobe Express” community science fair on Sept. 17 at the Warner Elementary Arts Magnet School in East Nashville.
Study identifies key player in T cell “education”
Sep. 1, 2022—New Vanderbilt research could inform therapeutic strategies for enhancing thymic function when desired — such as during aging, recovery from radiation therapy or chemotherapy, or other conditions that reduce T cell output.
Vanderbilt researchers discover how gut inflammation leads to bone loss
Aug. 25, 2022—Gastrointestinal inflammation, such as occurs in inflammatory bowel disease, triggers the expansion of a population of “bone-eating” cells, leading to bone loss.
Study describes how E. coli co-opts cells, causes recurrent UTIs
Aug. 25, 2022—Researchers at Vanderbilt University Medical Center have discovered why the uropathogenic bacterium E. coli, the leading cause of urinary tract infections, is so tenacious; their findings could lead to new ways to prevent recurrent UTIs.
Mathers Foundation award supports study of crosstalk between skeletal, immune systems
Jul. 7, 2022—Vanderbilt's Jim Cassat, MD, PhD, has received a three-year, $750,000 award from the G. Harold and Leila Y. Mathers Foundation to support research exploring the interplay between bone homeostasis and infectious disease.