monoclonal antibodies

December 20, 2018

2018 a year of growth, achievement for VUMC

The following is a roundup of the news that made headlines at Vanderbilt University Medical Center in 2018.

By Doug Campbell
December 6, 2018

Discovery could lead to neutralizing West Nile virus

Researchers at Vanderbilt University Medical Center and colleagues have isolated a human monoclonal antibody that can “neutralize” the West Nile virus and potentially prevent a leading cause of viral encephalitis (brain inflammation) in the United States.

By Bill Snyder
September 6, 2018

Link between immune system, disease explored

The first Flexner Discovery Lecture of the academic year featured presentations by two Vanderbilt faculty members.

By Leigh MacMillan
August 30, 2018

Team isolates antibodies that neutralize GI bug norovirus

Researchers at Vanderbilt University Medical Center have isolated the first human monoclonal antibodies that can neutralize norovirus, the leading cause of acute gastrointestinal illness in the world.

By Bill Snyder
August 23, 2018

Madhur, Smith set to deliver fall season’s first Discovery Lecture

The Flexner Discovery Lecture series kicks off the academic year next week with presentations by two Vanderbilt faculty members. The Cutting-Edge Discovery Lectures by Meena Madhur, MD, PhD, and Scott Smith, MD, PhD, begin at 4 p.m. on Thursday, Aug. 30 in 208 Light Hall.

By Leigh MacMillan
July 19, 2018

Team finds potent antibodies against three Ebola viruses

Researchers at Vanderbilt University Medical Center and their colleagues are a step closer to developing a broadly effective antibody treatment against the three major Ebola viruses that cause lethal disease in humans.

By Bill Snyder
May 17, 2018

Alphavirus “Achilles heel”

Targeting the protein that mosquito-borne viruses use to enter cells could be a strategy for preventing infection by multiple emerging viruses.
By Bill Snyder
April 26, 2018

Study seeking to isolate antibodies against rabies virus

Few people die from rabid animal bites in the United States thanks to the near-universal availability of human rabies immune globulin and rabies vaccine, which are given as separate shots as soon as possible after exposure to the rabies virus.
By Bill Snyder
February 23, 2018

Hope for an RSV vaccine

Newly discovered features in an RSV protein may be useful for rational structure-based vaccine design.
By Bill Snyder
January 11, 2018

VUMC joins national effort to block global pandemics of potentially lethal viruses

The U.S. Defense Advanced Research Projects Agency (DARPA) has signed a five-year cooperative agreement worth up to $28 million with Vanderbilt University Medical Center (VUMC) to develop methods for preventing the global spread of viruses like chikungunya and Zika.
By Bill Snyder
December 14, 2017

Crowe elected a fellow of the National Academy of Inventors

James Crowe Jr., MD, director of the Vanderbilt Vaccine Center at Vanderbilt University Medical Center (VUMC), has been named a fellow of the National Academy of Inventors (NAI).
By Bill Snyder
October 17, 2017

Researchers find novel mechanism of resistance to anti-cancer drugs

Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance.
By Leigh MacMillan
October 12, 2017

Researcher targets peanut allergies with Cohen Fund support

Scott Smith, M.D., Ph.D., assistant professor of Medicine, has received a 2017 research award from the Stanley Cohen Innovation Fund to test a new therapeutic strategy for peanut allergies. Smith's research could fundamentally change allergy treatment.
By Leigh MacMillan
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